Comparative analysis of risk factors for COVID-19 mortality before, during and after the vaccination programme in Mexico

摘要: ObjectivesThe purpose of this study was to compare case fatality rates (CFRs) and odds for mortality by risk factors of patients with COVID-19 in Mexico, before, during and after the implementation of the national COVID-19 vaccination programme.Study designA large database including COVID-19 monitoring cases was used to perform an observational retrospective study.MethodsThe Chi-squared test and multivariate logistic regression analyses were applied to data from COVID-19-positive patients in Mexico. Data were analysed over 3 years, 2020, 2021 and 2022, corresponding with pre-, during and post-vaccination periods. The unadjusted odds ratios and 95% confidence interval were used to estimate the risk factors for COVID-19 mortality in each of the years.ResultsStatistically significant differences in CFR and odds ratio were found in the studied years, favouring postvaccination period. Significant changes …