P-678 Predictive value of intra-cycle FSH measurements for blastocyst euploid rate: a longitudinal cohort study

摘要: Study question Can intra-cycle FSH levels measured at baseline, mid-cycle, and on trigger day predict blastocyst euploid rate? Summary answer Repeat measurements of FSH were not useful for predicting the euploid rate of blastocysts after accounting for the effects of female age. What is known already During the follicular phase of ovarian stimulation cycles, blood FSH levels are kept at supraphysiologic levels for a longer period compared to naturally occurring ovulation cycles during which FSH levels recede in response to rising estradiol. Some studies suggested maintaining higher than necessary blood FSH concentrations may have a detrimental effect on embryo quality and ploidy and recommended intra-cycle FSH monitoring. Whether intra-cycle measurements of FSH can be used to predict euploid rate is yet to be determined. Study …