Oxidative potential and health risk assessment of ambient fine particulate matter around an opencast coal mining area in India

摘要: BACKGROUND AND AIM Particulate matter (PM2.5) exposures are prominent around opencast coal mining areas due to heavy transportation and mining activities. However, the toxicity of fine PM in mining communities, especially in India, is not well understood. This study aims to examine the oxidative potential (OP) of PM2.5 as an indicator for oxidative stress for better understanding of the health risks associated with exposure. METHOD PM2.5 was collected from roadsides and residential sites near an active coal mining area in Eastern Maharashtra, India. Oxidative potential of PM to examine the generation of reactive oxygen species (ROS) was carried out by dithiothreitol (OPDTT) and ascorbic acid (OPAA) assay. Further, inhalation health risk (USEPA IRIS), and PM2.5 bound water-soluble metals (through ICP-MS) were also examined. RESULTS PM2.5 levels at coal-haul road were 10 times higher than the …