作者: WI Abdulmajeed , HB Sulieman , MO Zubayr , Abubakar Ayinla Imam , A Amin
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摘要: This study investigates the protective potential of honey against lead-induced renal dysfunction. Thirty-two male Wistar rats were used, and they were divided into 4 groups AD (n= 8). The control group (A) were given lml/kg distilled water orally; Lead group (B) received 0.2% lead acetate in drinking water; Group (C) and Group (D) rats were given 0, 2% lead acetate in drinking water and 10 ml/kg and 1.5 ml/kg natural honey respectively for 4 weeks. At the end of the cxposure period, animals were sacrificed, blood samples were collected and centrifuged. The plasma was thereafter separated for measurements of blood urea and creatinine. Also right kidneys were excised and homogenized in 0.25 M sucrose solution. The homogenate was centrifuged and supernatants collected for estimation of total protein, malondialdehyde (MDA), antioxidant levels: reduced gluthatione (GSH), gluthationc s-transferase (GST …