Dietary evaluation, antioxidant and cytotoxic activity of crude extract from chia seeds (Salvia hispanica L.) against human prostate cancer cell line (PC-3)

摘要: Natural products have continually played an important role in drug discovery because it serves as active principles in drugs as well as templates for synthesis of new drugs. Present study is attempted to evaluate the dietary evaluation, antioxidant property and cytotoxicity (human prostate cancer cells) of crude extract of Chia seeds. Results, phytochemical screening and dietary evaluation revealed the presence of tanins, saponins, flavonoids, alkaloids, proteins, cardio glycosides, phenols and important minerals were present in the crude extract of Chia seeds. The total estimation of secondary metabolites of chia seed were found to be in moderate level. The cytotoxicity assay exposed that, crude extract of chia seeds inhibited the growth of prostate cancer cell lines (PC-3) in a dose dependent manner. In conclusion, the crude extract of Chia seeds can be used as a therapeutic option in prostate cancer cells. However, further studies are warranted to substantiate the current findings.