Integrating Live-Cell Imaging with Magnetic Manipulation System

摘要: The internalization of magnetic nanorobots within live cells provides insights into their behaviour under the influence of an external magnetic field. However, the heat generated by the Helmholtz coil poses a significant challenge, leading to cell death. Most commercially available systems rely on metallic components to facilitate heat transfer. However, if these systems are placed inside the triaxial Helmholtz coil of the experimental setup, the following magnetic field will create eddy currents, leading to unintended heating consequences. Additionally, the limited space inside the Helmholtz coil presents a significant constraint for accommodating commercial systems. Integrating standard commercial live cell setups with magnetic propulsion setups, typically composed of triaxial Helmholtz, poses challenges. Additionally, thermal control is crucial as temperature maintenance within a degree is necessary, despite …