Histone acetyltransferase (hat) regulators and uses thereof

作者: Ottavio Arancio , Donald W. Landry , Shixian Deng , Jennifer Effie AMENGUAL , Elisa Zuccarello

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摘要: The invention provides for compounds that are HAT acti vators or inhibitors. The invention further provides a method for treating neurodegenerative diseases, cancer and other malignant conditions, or to increase memory in a subject not suffering from a neurodegenerative disease by administering HAT activators or inhibitors to a subject in need thereof. The method further comprises co-administration of HD AC inhibitors with HAT activators or HD AC activators with HAT inhibitors.

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