A clinico-pathologic study of neoplastic epithelial salivary gland tumours seen over 15 years at a Nigerian tertiary centre

摘要: OBJECTIVES: The aim of this study was to review the clinicopathologic characteristics of neoplastic epithelial salivary gland tumours (SGTs) and update current information available on clinicopathology of the SGTs based on WHO, 2017 classification.METHODS: A 15-year retrospective review of the clinicopathology of specimens, using biopsy reports and histopathology slidesneoplastic epithelial SGTs seen in the Oral Pathology unit of the Department of Oral Maxillofacial Surgery & Oral pathology, and the Department of Morbid Anatomy & Forensic Medicine, ObafemiAwolowo University Teaching Hospitals Complex Ile-Ife. The age, gender, site, histopathologic type and subtype of tumours were analysed.RESULTS: A total of 125 (5.2%) SGTs were seen among 2,404 head and neck tumours seen over the study period. One hundred and twenty two (97.6%) of these were neoplastic epithelial SGTs. Most of theneoplastic epithelial SGTs were benign lesions (63.1%) consisting mostly pleomorphic adenoma (PA) accounting for 53.3% of all neoplastic epithelial SGTs. Mucoepidermoidcarcinoma (MEC) and adenoid cystic carcinoma (AdCC) were the commonest malignant epithelial SGTs, each accounting for 14.8% of all theneoplastic epithelial SGTs. The mean age of the patients was 42.5±18.0 years. There was female predominance with a female to male ratio of 1.5: 1. The major salivary glands (73.8%) were the commonest site with the parotid glandrecording the highest occurrence (55.7%). The palate was the commonest intraoral site observed (16.4%).CONCLUSION: This study observed that pleomorphic adenoma was the commonest …