Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation

作者: Vincent Sandanayaka , Jasbir Singh , Mark Gurney , Bjorn Mamat , Peng Yu

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摘要: The present invention relates to a chemical genus of biary1 substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and pro phylaxis of inflammatory diseases and disorders. The com pounds have general formula:

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