Deferral due to low hemoglobin and predictors of permanence in the blood donation system of repeat female blood donors

摘要: ObjectivesTo evaluate the deferral rate due to low hemoglobin (Hb) in repeat female blood donors and identify the factors affecting their permanence in the blood donation system.Materials and methods8,368 repeat female blood donors who donated from January 2012 to December 2018 were included. Bivariate analysis and Kaplan-Meier curves were used to identify the covariates possibly associated with developing low Hb, and Cox proportional hazards modeling was used to adjust for all confounders.ResultsThe global deferral rate due to low Hb was 2.4 %. According to baseline Hb, the frequency of low Hb was 0.7–4.1 %, and it was higher in platelet donors (5.8–9.1 %) than in whole blood donors (1.9 %). The main predictors were baseline Hb (compared to the first quartile; hazard ratio [HR] = 0.487 for the second quartile; 0.234 for the third; and 0.095 for the fourth); change in Hb (HR = 2.689 for a >0.49 …