P185 Evaluation of myocardial strain assessed by CMR tissue-tracking to predict adverse cardiovascular events in patients with cardiac amyloidosis

摘要: INTRODUCTION Cardiac amyloidosis is the most frequent cause of restrictive cardiomyopathy. CMR is the most important technique used to diagnose cardiac involvement and the amount of LGE is associated with a worse prognosis. The role of other CMR derived parameters such as myocardial deformation are still unknown. The aim of this study is to analyze the prognostic implication of different CMR parameters, including tissue-deformation in patients with cardiac amyloidosis. METHODS We recruited 53 patients, with histologically proven amyloidosis, prospectively followed in our cardiomyopathy unit, from 2010 to 2017. Patients were included after an echocardiography positive study of cardiac involvement. The patients underwent a CMR evaluation: left ventricular volumes, ejection fraction, mass, and deformation (radial, circumferential and longitudinal strain) were assessed using cine sequences. LGE …