摘要: Multiple treatment approaches have evolved for the management of diabetic macular edema. While anti-VEGF therapy seems to be promising, 1 according to leading researchers, a “VEGF+” approach might be more effective, particularly in the case of DME, compared to the VEGF-only approach, which is more relevant for the management of AMD.In keeping with this concept, researchers have been searching for new molecular targets other than VEGF to make DME therapy more effective. This article provides detailed information regarding newer molecular targets that have appeared promising in early clinical trials.