摘要: * Brooklyn, NY,, USA whether they result from synucleinopathy, tauopathy (supranuclear palsy), or Par! dne gone mutation, but also in abnormal daytime sleep onset in REM periods. These" narcoleptic-like" episodes may cause awakening dreams (hypnagogic hallucinations), and sleep attacks. The narcolepsy-like pattern (but not RBD) can be reproduced in animal models of PD, suggesting that the dopaminergic depletion partly causes it. Dopaminergic drugs have stimulant or on tile contrary sedative effects, but tile reason for this last unexpected effect in some patients remains unknown, although it is more frequently observed in patients with more advanced disease. Removal or replacement of a recently-introduced dopamine agonist may relieve daytime sleepiness. If not, the adjunction of modafinil, that shows neuro-protective effects in parkinsonian animals, has a good benefit/risk ratio in patients with PD.