Co (II) and Cu (II) complexes of oxime hydrazone derivative: Structural, geometrical, biological studies and ion-flotation separation of Cu (II) ions.

摘要: Co (II) and Cu (II) complexes enclosing xime hydrazone ligand (H4MDO) prepared via the condensation of malonohydrazide with diacetyl monoxime were synthesised and characterized using elemental analysis, magnetic and spectral measurements. The proposed tetrahedral structures of both complexes were proved using DFT optimization and conformational analysis. The thermal decomposition behaviour of complexes were discussed. Kinetic parameters (∆ H,∆ S,∆ G, E and A) of resulted thermal decomposition stages have been calculated using Coats-Redfern and Horowitz-Metzger methods. Ion-flotation separation of Cu (II) ions was carried out from aqueous solutions using oxime derivative as chelating agent and oleic acid as surfactant. H4MDO shows the highest minimum inhibitory concentration (MIC) activity of Co (II) complex against Staphylococcus aureus, Escherichia coli and Candida albicans. Cytotoxicity assay of the above complexes revealed the higher activity of H4MDO and Co (II) complex than Cu (II) complex.