Biomechanical Analysis of a Critical-Size Canine Femoral Segmental Defect Reconstructed with a Titanium Mesh Cage

摘要: The treatment of large diaphyseal defects remains a formidable clinical challenge. A critical-size defect, which has been defined as one which will not heal without augmentation is typically of length about 2.5-3 times the external diameter of the intact bone.[1] Cylindrical meshed titanium cages filled with bone graft have been successfully used in the spine to replace and/or fuse vertebral bodies. This technique has been used clinically to address critical-size segmental long bone diaphyseal defects.[2] The healing potential of this construct has yet to be accurately determined.OBJECTIVES: