ESOPHAGEAL CANDIDIASIS AND HELICOBACTER PYLORI INFECTION

摘要: Introduction There is few published data about the correlation of helicobacter pylori infection and esophageal candidiasis. This study was designed to investigate the prevalence of helicobacter pylori infection in patients with and without esophageal candidiasis. Methods Endoscopic and histologic documentation of consecutive dyspeptic patients were evaluated for detection of prevalence of helicobacter pylori infection in patient with and without esophageal candidiasis. Esophageal candidiasis was diagnosed based on classic findings of esophageal white plaques (thrush). Helicobacter pylori infection was diagnosed based on staining with haematoxylin and eosin stain on samples of antral biopsy of stomach. Results 28 (16 female and 12 male) patients with esophageal candidiasis and 1996 (1295 female and 701 male) patients without esophageal candidiasis were conducted in this study. The mean age (SD) of patients with and without esophageal candidiasis was 55.57 (16.79) and 42.65 (17.12) years old, respectively. Helicobacter pylori infection was detected in 19 (67.9%) and 1502 (75.25%) of patients with and without esophageal candidiasis, respectively. There was not any significant relationship in prevalence of helicobacter pylori between two groups (OR 1.44; 95% CI 0.6474, 3.204; p= 0.3687; Chi Square test). There was not also any significant relationship in prevalence of helicobacter pylori after matching of age in two groups (OR 0.7; p= 0.38; Regression analysis). Conclusion We suggest that there is no correlation between the existence of helicobacter pylori infection and esophageal candidiasis. Based on our result detection of …