Evaluation of the Effectiveness of Mindfulness-based Stress-reduction Training Program on Decreasing Depression and Anxiety Symptoms in Patients with Non-alcoholic Fatty liver

摘要: Introduction Depression and anxiety are highly prevalent in patients with non-alcoholic fatty liver disease, reducing mental health and leading to dysfunction in various dimensions. Due to the significant role of psychological factors in the process of treatment and recovery of patients, this study was conducted to determine the effectiveness of the mindfulness-based stress-reduction training program on decreasing depression and anxiety symptoms in patients with non-alcoholic fatty liver.Materials and Methods This randomized clinical trial study was performed in 2018 on 30 patients with non-alcoholic fatty liver disease referred to Ghadir specialized clinic in Aligudarz city. Subjects were randomly divided into two experimental and control groups (15 people in each). Mindfulness-Based Stress-Reduction (MBSR) training was conducted for the experimental group during 8 weekly sessions (each lasting 45 to 90 minutes). The control group did not receive any intervention. The data collection tool was Depression, Anxiety, and Stress Scale (DASS). Data were analyzed using two-way repeated-measures ANOVA by SPSS software version 24.Results The results of two-way repeated-measures ANOVA showed a significant difference between the mean scores of the experimental and control groups in depression (p<0.001, F = 74.125 and η = 0.726) and anxiety (p<0.001, F = 015/158 and η = 0.849). Thus, the score of depression and anxiety of people with fatty liver in the experimental group after mindfulness training significantly decreased compared to the control group.Conclusion According to the obtained results, the mindfulness-based stress-reduction …