In vitro antifungal activity of methanolic extract of various parts of Punica granatum L

作者: Mahsa Shafighi , Leila Amjad , Mahboobeh Madani

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摘要: Candida species are now fourth common organisms isolated from hospitalized patients. It is important to increase effective therapy. In the past decade numerous reports of treatment failures are reported. In the other hand, plants have been used for thousands of years to flavor and conserve food, to treat health disorders and to prevent diseases including epidemics. The aim of this study was to investigate the antifungal effect of methanolic extract of pomegranate peel, flower, leaf and stem against Candida albicans NCPF 3153 by well diffusion, also MIC snd MFC were determined. Punica granatum L. was collected from Isfahan, Iran. All part of plants were dried and pwodred seperatly. The dried powders were extracted by Soxhlet apparatus for 8 hours. Results showed that maximum inhibition zones of antifungal effect were obtained in 200 µl concentration by flower extract. This provides a complementary preventive value for this plant and supports its gaining popularity as an antifungal source.

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