Electrochemical Bromination of Substituted Thiophenes in Batch and Continuous Flow

摘要: An electrochemical bromination of thiophenes from ammonium bromide is developed both in batch and continuous‐flow conditions. Substituted thiophenes possessing 2‐hydrogens selectively afford a series of 2‐bromothiophenes while 2‐substituted benzothiophenes generate 3‐bromobenzo[b]thiophenes. Based on the cyclic voltammetric studies and literature, a bromine cation involved mechanism was proposed.