Primary Squamous Cell Carcinoma of the Gallbladder: Case Report

作者: Sahar Dashti , Elahe Mirzaee , Maryam Garousi , Mastaneh Sanei , Navid Abdi

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摘要: Pure gallbladder squamous cell carcinoma is rare. Adenocarcinoma is the foremost malignant pathology of gallbladder cancer. Simultaneously, squamous cell carcinoma accounts for only< RL1% of malignant gallbladder tumors. They are often advanced at diagnosis and associated with poor prognosis. The patient was a 37-year-old man diagnosed with poorly differentiated squamous cell carcinoma of the gallbladder. He underwent Cholecystectomy, right hemicolectomy, hepatic wedge resection, and regional lymph node dissection and received six courses of adjuvant chemotherapy with FOLFOX. After two months, liver metastasis was diagnosed, and a chemotherapy regimen consisting of gemcitabine cisplatin pembrolizumab was started. After three courses, stable disease was seen.Conclusion: Surgery is the main treatment. There is no consensus about the best adjuvant treatment. The results obtained from this patient might help the role of adjuvant therapies in treating this rare case report.

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