Predictiveness of preoperative laboratory values for postoperative delirium

摘要: Background Postoperative delirium (POD) is a common postoperative complication, especially in patients over 60 years, with an incidence ranging from 15% to 50%. In most cases, POD manifests in the first 5 days after surgery. Multiple contributing risk factors for POD have been detected. Besides the predisposing factors such as higher age, cognitive impairment, high blood pressure, atrial fibrillation, and past stroke, pathophysiological mechanisms like neuroinflammation are also considered as contributing factors. Methods In a subanalysis of the “PRe‐ Operative  Prediction of postoperative  DElirium by appropriate  SCreening” (PROPDESC) study, the preoperative laboratory values of sodium, potassium, total protein, hemoglobin concentration (Hgb), and white blood cells as well as the biomarkers creatinine, HbA1c, NT‐pro‐BNP, high sensitive Troponin T (hsTnT), and C‐reactive protein (CRP) were assessed …