SOP Title Muscle function evaluation through isometric force measurement in mouse models of spinal muscular atrophy

摘要: 1. OBJECTIVEThis document aims to provide instructions on how to measure isometric muscle tension elicited by nerve (indirect) and muscle (direct) stimulation from extensor digitorum longus (EDL) muscle in a mouse model (SMNΔ 7) of spinal muscular atrophy (SMA).