The role of curcumin in ameliorating learning and memory disorders.

摘要: Curcumin is an active yellow substance extracted from the rhizome of Curcuma longa (turmeric). In recent years, curcumin has been reported to have anti-cancer, liver protection, thrombus inhibitor, cardiovascular and anti-arthritis effects. Curcumin has been also known to modulate intracellular signaling pathways that control cell growth, inflammation, and apoptosis (programmed cell death). Curcumin is a powerful antioxidant that reduces circulating free radicals and due to its antioxidant and anti-inflammatory activities can be a potential candidate for the prevention or treatment of neurological diseases and memory disorders. The results of studies in rodents (without induction of memory impairment) have shown that certain doses of curcumin improve memory function. It has been reported that curcumin can prevent and improve age-related memory impairment as one of the causes of irreversible memory …