Does hypocapnia prevent modification in cerebral blood flow velocity in children when changing from sevoflurane to desflurane anesthesia?: A-564

摘要: Materials and Methods: With REB approval 10 healthy children scheduled for urological surgery were enrolled. Each patient randomly received Sev 1 MAC at either 30 or 40 mmHg end-tidal CO 2 (ETCO 2) followed by Des 1 MAC at the same ETCO 2. The same sequence was repeated at the other ETCO 2. CBFV was measured at steady-state for each agent and ETCO 2. Heart rate, mean arterial blood pressure and temperature were recorded.Results and Discussions: The age and weight were 36.6±23.8 mo and 14.3±5.2 kg, respectively. CBFV was higher at ETCO 2 40 when compared to ETCO 2 30 regardless of the anesthetic agent.(P< 0.001, Table) The blood pressure decreased when sevoflurane was switched to desflurane at 30 mmHg ETCO 2 and HR remained unchanged (P< 0.01, Table).