FRENCH MYELOID DATABASE: RELEVANT TOOL FOR ANTICIPATION THE MOST FREQUENT RECURRENT GENETIC ABNORMALITIES AND TO IMPROVE THE ACUTE MYELOID LEUKAEMIA DIAGNOSTIC

摘要: Results. Initial results showed that the CD34+ and CD34-/CD117+ neutrophil precursors are the most useful for building a myeloid database, proving remarkable applicability and outstanding reproducibility for anticipation of the most frequent recurrent genetic abnormalities. No differences of reproducibility were observed between the two types of precursors and the most discriminative markers are: FSC, SSC, HLA-DR, CD117, CD13 and CD11b. Conclusion. The Myeloid Database is a comprehensive visualization interface that can make it useful as a daily tool for pathologists and cancer researchers to expand repertoire of testing capability for diagnostic, prognostic and therapeutic applications of myeloid leukemic malignancies.