2078. Comparison of Complication Types in Patients Receiving Vesicant Intravenous Antimicrobials or Vasopressors via Midlines and PICCs: A Retrospective Review

摘要: Background Peripherally inserted central catheters (PICC) are frequently used for long-term intravenous access in hospitalized patients; however, their use is associated with an increased risk of catheter-related bloodstream infection (CRBSI). Midline catheters (MC) have emerged as a potentially safer alternative and are associated with reduced rates of CRBSI but increased risk of thrombosis. Until recently, the use of several vasopressors and antibiotics via MC has been limited due to unknown adverse events. We aimed to compare the hazard ratios for CRBSI, thrombosis, catheter occlusion, and overall adverse events (AE) in adult intensive care unit (ICU) patients receiving vesicant antibiotics or vasopressors through PICC or MC. Methods We reviewed patients in 13 ICUs at one quaternary care center from April 2021 to September 2022 who received selected vesicant …