CSIG-35. MST4 PHOSPHORYLATION OF ATG4B REGULATES AUTOPHAGIC ACTIVITY, TUMORIGENICITY, AND RADIORESISTANCE IN GLIOBLASTOMA

Tianzhi Huang , Chung Kwon Kim , Angel Alvarez , Rajendra Pangeni
Neuro-oncology 20

2018
Tumour-specific Causal Inference Discovers Distinct Disease Mechanisms Underlying Cancer Subtypes

Yifan Xue , Gregory Cooper , Chunhui Cai , Songjian Lu
Scientific Reports 9 ( 1) 13225

2019
GOGrapher: A Python library for GO graph representation and analysis

Brian Muller , Adam J Richards , Bo Jin , Xinghua Lu
BMC Research Notes 2 ( 1) 122 -122

8
2009
Learning to encode cellular responses to systematic perturbations with deep generative models.

Yifan Xue , Michael Q. Ding , Xinghua Lu
npj Systems Biology and Applications 6 ( 1) 35 -35

1
2020
A comparative analysis of methods for predicting clinical outcomes using high-dimensional genomic datasets

Xia Jiang , Binghuang Cai , Diyang Xue , Xinghua Lu
Journal of the American Medical Informatics Association 21

8
2014
Estrogen represses gene expression through reconfiguring chromatin structures

Hatice Ulku Osmanbeyoglu , Kevin N. Lu , Steffi Oesterreich , Roger S. Day
Nucleic Acids Research 41 ( 17) 8061 -8071

13
2013
Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference

Chunhui Cai , Gregory F Cooper , Kevin N Lu , Xiaojun Ma
PLOS Computational Biology 15 ( 7)

13
2019
Trans-species learning of cellular signaling systems with bimodal deep belief networks

Lujia Chen , Chunhui Cai , Vicky Chen , Xinghua Lu
Bioinformatics 31 ( 18) 3008 -3015

25
2015
Discovering functional impacts of miRNAs in cancers using a causal deep learning model

Lujia Chen , Xinghua Lu
BMC Medical Genomics 11 ( 6) 116

2
2018
Functional MRI Detection of Deception After Committing a Mock Sabotage Crime

F. Andrew Kozel , Kevin A. Johnson , Emily L. Grenesko , Steven J. Laken
Journal of Forensic Sciences 54 ( 1) 220 -231

49
2009
19
2010
Assessing the functional coherence of gene sets with metrics based on the Gene Ontology graph

Adam J. Richards , Brian Muller , Matthew Shotwell , L. Ashley Cowart
Bioinformatics 26 ( 12) 79 -87

31
2010
Unexpected Mobility Variation among Individual Secretory Vesicles Produces an Apparent Refractory Neuropeptide Pool

Yuen-Keng Ng , Xinghua Lu , Alexandra Gulacsi , Weiping Han
Biophysical Journal 84 ( 6) 4127 -4134

22
2003
The center for causal discovery of biomedical knowledge from big data

Gregory F Cooper , Ivet Bahar , Michael J Becich , Panayiotis V Benos
Journal of the American Medical Informatics Association 22 ( 6) 1132 -1136

20
2015
Probing Biomedical Embeddings from Language Models

Qiao Jin , Bhuwan Dhingra , William Cohen , Xinghua Lu
workshop on evaluating vector space representations for nlp 82 -89

97
2019
Deep Contextualized Biomedical Abbreviation Expansion.

Qiao Jin , Jinling Liu , Xinghua Lu
meeting of the association for computational linguistics 88 -96

33
2019
Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations.

Songjian Lu , Chunhui Cai , Gonghong Yan , Zhuan Zhou
Cancer Research 76 ( 23) 6785 -6794

3
2016
Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma

Hirokazu Sadahiro , Kyung-Don Kang , Justin T Gibson , Mutsuko Minata
Cancer Research 78 ( 11) 3002 -3013

99
2018
MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

Tianzhi Huang , Chung Kwon Kim , Angel A. Alvarez , Rajendra P. Pangeni
Cancer Cell 32 ( 6) 840

152
2017