Massively Parallel Protein Design to Develop Enzymes for Next-Generation Chemotherapy

Brahm Yachnin , Victor Tan , Laura Azouz , Justin Drake
PROTEIN SCIENCE 27 108 -108

2018
An integrated computational-experimental approach for designing photoswitchable protein assemblies

Elliott Dolan , Srinivas Mushnoori , Meenakshi Dutt , Sagar Khare
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256

2018
Large-scale prediction, characterization and modulation of protease enzyme specificity landscape using computation and experiment

Sagar Khare , Sagar Khare , Manasi Pethe , Aliza Rubenstein
PROTEIN SCIENCE 26 55 -56

2017
Illuminating the Specificity Landscape of the HCV NS3 Protease using Computation and Next Generation Sequencing

Manasi Pethe , Aliza Rubenstein , Sagar Khare , Dmitri Zoraine
PROTEIN SCIENCE 26 171 -171

2017
Structure-based predictive model for the substrate specificity of the tobacco etch virus protease

Marissa Saladin , Manasi Pethe , Sagar Khare
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247

2014
Biophysical mechanisms of protein aggregation

Sagar Khare
The University of North Carolina at Chapel Hill

2006
Novel method for detecting protein folding intermediates provides insight into the role of conformational dynamics in cell adhesion proteins

Richard DS Dixon IV , Yiwen Chen , Feng Ding , Sagar Khare
The 56th Southeast Regional Meeting 2004

2004
Designer Quorum Quenching Enzymes for Synthetic Biology and Therapeutics

Anish Vaghela , Deepak Gupta , Johnlevi Lazaro , John Bender

RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular

SJ Fleishman , A Leaver-Fay , JE Corn , EM Strauch

2011
Probing the Mechanism of Lys-to-Trp Crosslink Formation Catalyzed by a New Class of Radical SAM Enzymes

KR Schramma , LB Bushin , MR Seyedsayamdost , KM Davis
Discovery of a Family of Radical S-Adenosylmethionine Enzymes that Install a Novel Lysine-to-Tryptophan Crosslink 108 -108

2017
Characterization of a New Family of Radical SAM Enzymes that Install an Unusual Lys-to-Trp Crosslink

KR Schramma , LB Bushin , MR Seyedsayamdost , KM Davis
Discovery of a Family of Radical S-Adenosylmethionine Enzymes that Install a Novel Lysine-to-Tryptophan Crosslink 35 -35

2017
The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis

S. D. Khare , M. Caplow , N. V. Dokholyan
Proceedings of the National Academy of Sciences of the United States of America 101 ( 42) 15094 -15099

130
2004
Common dynamical signatures of familial amyotrophic lateral sclerosis-associated structurally diverse Cu, Zn superoxide dismutase mutants

S. D. Khare , N. V. Dokholyan
Proceedings of the National Academy of Sciences of the United States of America 103 ( 9) 3147 -3152

81
2006
Molecular Dynamics Simulation of Amyloid β Dimer Formation

B. Urbanc , L. Cruz , F. Ding , D. Sammond
Biophysical Journal 87 ( 4) 2310 -2321

170
2004
2020