Frank McCormick
机构: Professor of Biochemistry, UCSF
每年引用次数
引用次数
引用: 101,608
H-指数: 144
I10-指数 : 394
出版物: 765
EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function
Janyaporn Phuchareon , Frank McCormick , David W. Eisele , Osamu Tetsu
Proceedings of the National Academy of Sciences of the United States of America 112 ( 29) 201510733
57
2015
CANCER THERAPY BASED ON THE Ras PATHWAY
Frank McCormick , Madhu Macrae , Osamu Tetsu , Pablo Rodriguez-Viciana
Cold Spring Harbor Symposia on Quantitative Biology 70 ( 1) 1 -1
1
2005
Brefeldin A: the advantage of being uncompetitive.
Pierre Chardin , Frank McCormick
Cell 97 ( 2) 153 -155
322
1999
The Human p62 cDNA Encodes Sam68 and Not the RasGAP-Associated p62 Protein
Peter Lock , Stefano Fumagalli , Paul Polakis , Frank McCormick
Cell 84 ( 1) 23 -24
67
1996
Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization
Marc Symons , Jonathan M.J Derry , Brian Karlak , Sharon Jiang
Cell 84 ( 5) 723 -734
775
1996
Immunological cross-reaction between large T-Antigens of SV40 and polyoma vir
Frank McCormick , David P. Lane , Stephen M. Dilworth
Virology 116 ( 1) 382 -387
3
1982
Chromosome aberrations in solid tumors.
Donna G Albertson , Colin Collins , Frank McCormick , Joe W Gray
Nature Genetics 34 ( 4) 369 -376
672
2003
Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours.
Eitan Friedman , Pablo V. Gejman , George A. Martin , Frank McCormick
Nature Genetics 5 ( 3) 242 -247
54
1993
Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication.
Clodagh O'Shea , Kristina Klupsch , Serah Choi , Bridget Bagus
The EMBO Journal 24 ( 6) 1211 -1221
105
2005
Phosphorylation-independent Stabilization of p27kip1 by the Phosphoinositide 3-Kinase Pathway in Glioblastoma Cells
Christian H. Brandts , Benoit Bilanges , Gregor Hare , Frank McCormick
Journal of Biological Chemistry 280 ( 3) 2012 -2019
8
2005
Ras p21: effects and regulation
Heinz Haubruck , Frank McCormick
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1072 ( 2-3) 215 -229
70
1991
Phosphoinositide 3-OH Kinase (PI3K) and PKB/Akt Delay the Onset of p53-mediated, Transcriptionally Dependent Apoptosis
Peter Sabbatini , Frank McCormick
Journal of Biological Chemistry 274 ( 34) 24263 -24269
133
1999
The duality of human oncoproteins: drivers of cancer and congenital disorders.
Pau Castel , Katherine A. Rauen , Frank McCormick
Nature Reviews Cancer 20 ( 7) 383 -397
8
2020
Replicating viruses as selective cancer therapeutics.
David H. Kirn , Frank McCormick
Molecular Medicine Today 2 ( 12) 519 -527
125
1996
Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior
Debanjan Goswami , De Chen , Yue Yang , Prabhakar R Gudla
eLife 9
4
2020
Costello and cardio-facio-cutaneous syndromes: Moving toward clinical trials in RASopathies
Katherine A. Rauen , Anuradha Banerjee , W. Robert Bishop , Jennifer O. Lauchle
American Journal of Medical Genetics Part C: Seminars in Medical Genetics 157 ( 2) 136 -146
34
2011
RAS-targeted therapies: is the undruggable drugged?
Amanda R. Moore , Scott C. Rosenberg , Frank McCormick , Shiva Malek
Nature Reviews Drug Discovery 19 ( 8) 533 -552
449
2020
PIK3CA Cooperates with Other Phosphatidylinositol 3′-Kinase Pathway Mutations to Effect Oncogenic Transformation
Katsutoshi Oda , Jennifer Okada , Luika Timmerman , Pablo Rodriguez-Viciana
Cancer Research 68 ( 19) 8127 -8136
178
2008
Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition
Olga K. Mirzoeva , Debopriya Das , Laura M. Heiser , Sanchita Bhattacharya
Cancer Research 69 ( 2) 565 -572
416
2009
Targeted phosphoproteomics of the Ras signaling network reveal regulatory mechanisms mediated by oncogenic KRAS
Anatoly Urisman , Tina L Yuan , Marena Trinidad , John H Morris
bioRxiv 695460
2019