Titia K. Sixma
机构: Division of Biochemistry, Netherlands Cancer Institute, Amsterdam
每年引用次数
引用次数
引用: 22,359
H-指数: 70
I10-指数 : 116
出版物: 142
The three-dimensional structure of "escherichia coli" heat-labile enterotoxin in relation to its function
Titia Karen Sixma
s.n.
1992
The role of UBL domains in ubiquitin-specific proteases.
Alex C. Faesen , Mark P.A. Luna-Vargas , Titia K. Sixma
Biochemical Society Transactions 40 ( 3) 539 -545
90
2012
Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase.
Alex C. Faesen , Annette M.G. Dirac , Anitha Shanmugham , Huib Ovaa
Molecular Cell 44 ( 1) 147 -159
155
2011
Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G.
Danny D. Sahtoe , Willem J. van Dijk , Farid El Oualid , Reggy Ekkebus
Molecular Cell 57 ( 5) 887 -900
72
2015
Make them, break them, and catch them: studying rare ubiquitin chains.
Michael Uckelmann , Titia K. Sixma
Molecular Cell 58 ( 1) 1 -2
21
2015
The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types
Alex C. Faesen , Mark P.A. Luna-Vargas , Paul P. Geurink , Marcello Clerici
Chemistry & Biology 18 ( 12) 1550 -1561
205
2011
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
Francesca Mattiroli , Joseph H.A. Vissers , Willem J. van Dijk , Pauline Ikpa
Cell 150 ( 6) 1182 -1195
394
2012
Structure and function of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.
AUGUST B. SMIT , KATJUŠA BREJC , NAWEED SYED , TITIA K. SIXMA
Annals of the New York Academy of Sciences 998 ( 1) 81 -92
46
2003
The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains.
J A Marteijn , L T van der Meer , J J Smit , S M Noordermeer
Leukemia 23 ( 8) 1480 -1489
22
2009
AUGUST B. SMIT," KATJUŠA BREJC, b, c NAWEED SYED, d
TITIA K SIXMA
Myasthenia Gravis and Related Disorders: Biochemical Basis for Disease of the Neuromuscular Junction 998 81 -92
2003
X-Ray studies reveal lanthanide binding sites at the A/B5 interface of E. coli heat labile enterotoxin
Titia K. Sixma , Anke C. Terwisscha van Scheitinga , Kor H. Kalk , Kangjing Zhou
FEBS Letters 297 ( 1) 179 -182
4
1992
Heat-labile enterotoxin crystal forms with variable A/B5 orientation. Analysis of conformational flexibility
Titia K. Sixma , Angel Aguirre , Anke C.Terwisscha van Scheltinga , Ellen S. Wartna
FEBS Letters 305 ( 2) 81 -85
11
1992
Quantitative analysis of USP activity in vitro.
Shreya Dharadhar , Robbert Q. Kim , Michael Uckelmann , Titia K. Sixma
Methods in Enzymology 618 281 -319
3
2019
Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.
Joyce H. G. Lebbink , Alexander Fish , Annet Reumer , Ganesh Natrajan
Journal of Biological Chemistry 285 ( 17) 13131 -13141
43
2010
Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS
Maria Chiara Monti , Serge X. Cohen , Alexander Fish , Herrie H. K. Winterwerp
Nucleic Acids Research 39 ( 18) 8052 -8064
27
2011
Insight in nAChR subtype selectivity from AChBP crystal structures
Prakash Rucktooa , August B. Smit , Titia K. Sixma
Biochemical Pharmacology 78 ( 7) 777 -787
106
2009
Structural aspects of multi-domain RING/Ubox E3 ligases in DNA repair
Richard G. Hibbert , Francesca Mattiroli , Titia K. Sixma
DNA Repair 8 ( 4) 525 -535
14
2009
Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity
Robbert Q. Kim , Paul P. Geurink , Monique P. C. Mulder , Alexander Fish
Nature Communications 10 ( 1) 231 -231
9
2019
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases.
Mark P.A. Luna-Vargas , Evangelos Christodoulou , Andrea Alfieri , Willem J. van Dijk
Journal of Structural Biology 175 ( 2) 113 -119
66
2011
Transient transfection coupled to baculovirus infection for rapid protein expression screening in insect cells.
Stephan Radner , Patrick H.N. Celie , Karoline Fuchs , Werner Sieghart
Journal of Structural Biology 179 ( 1) 46 -55
28
2012