Michael Desai
机构: Professor of Organismic and Evolutionary Biology and of Physics, Harvard University
主页: harvard.edu
每年引用次数
引用次数
引用: 8,626
H-指数: 43
I10-指数 : 66
出版物: 94
Idiosyncratic epistasis leads to global fitness–correlated trends
Christopher W Bakerlee* , Alex N Nguyen Ba* , Yekaterina Shulgina , Jose I Rojas Echenique
Science 376 ( 6593) 630 -635
39
2022
Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations
Christopher W Bakerlee , Angela M Phillips , Alex N Nguyen Ba , Michael M Desai
Elife 10 e70918 -e70918
19
2021
The Genetic Basis of Differential Autodiploidization in Evolving Yeast Populations
Sudipta Tung , Christopher W Bakerlee , Angela M Phillips , Alex N Nguyen Ba
G3 11 ( 8)
6
2021
Inferring sparse structure in genotype–phenotype maps
Samantha Petti , Gautam Reddy , Michael M Desai
Genetics 225 ( 1) iyad127 -iyad127
4
2023
Epistasis and evolution: recent advances and an outlook for prediction
Milo S Johnson , Gautam Reddy , Michael M Desai
BMC Biology 21 ( 1) 1 -12
28
2023
Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody
Angela M Phillips , Daniel P Maurer , Caelan Brooks , Thomas Dupic
Elife 12 e83628 -e83628
11
2023
Genotype–phenotype landscapes for immune–pathogen coevolution
Alief Moulana , Thomas Dupic , Angela M Phillips , Michael M Desai
Trends in Immunology
5
2023
Spatial structure alters the site frequency spectrum produced by hitchhiking
Jiseon Min , Misha Gupta , Michael M Desai , Daniel B Weissman
Genetics 222 ( 3) iyac139 -iyac139
5
2022
Yeast population dynamics in Brazilian bioethanol production
Artur Rego-Costa , I Ting Huang , Michael M Desai , Andreas K Gombert
G3: Genes, Genomes, Genetics 13 ( 7) jkad104 -jkad104
3
2023
Haigh (1978) and Muller’s ratchet
Michael M Desai
Theor Popul Biol 133 19 -20
2
2020
Protein sequence landscapes are not so simple: on reference-free versus reference-based inference
Thomas Dupic , Angela M Phillips , Michael M Desai
bioRxiv 2024.01. 29.577800 -2024.01. 29.577800
1
2024
The influenza hemagglutinin stem antibody CR9114: evidence for a narrow evolutionary path towards universal protection
Anna L Beukenhorst , Jacopo Frallicciardi , Clarissa M Koch , Angela Phillips
Frontiers in Virology 93 -93
1
2022
Effects of selection stringency on the outcomes of directed evolution
Berk A Alpay , Michael M Desai
bioRxiv 2024.06. 09.598029 -2024.06. 09.598029
2024
A dynamical limit to evolutionary adaptation
Matthew J Melissa , Michael M Desai
Proceedings of the National Academy of Sciences 121 ( 4) e2312845121 -e2312845121
2024
Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations
B. H. Good , I. M. Rouzine , D. J. Balick , O. Hallatschek
Proceedings of the National Academy of Sciences of the United States of America 109 ( 13) 4950 -4955
170
2012
Distortions in Genealogies Due to Purifying Selection
L. E. Nicolaisen , M. M. Desai
Molecular Biology and Evolution 29 ( 11) 3589 -3600
33
2012
Flexible gene pools
M. M. Desai , A. M. Walczak
Science 348 ( 6238) 977 -978
2015
The Evolutionarily Stable Distribution of Fitness Effects
D. P. Rice , B. H. Good , M. M. Desai
Genetics 200 ( 1) 321 -329
29
2015
Global Epistasis Makes Adaptation Predictable Despite Sequence-Level Stochasticity
S. Kryazhimskiy , D. P. Rice , E. R. Jerison , M. M. Desai
Science 344 ( 6191) 1519 -1522
297
2014
Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes
Michael Baym , Sergey Kryazhimskiy , Tami D. Lieberman , Hattie Chung
PLOS ONE 10 ( 5) e0128036
366
2015
Benjamin H Good Sergey Kryazhimskiy Daniel P Rice Daniel S Fisher Elizabeth Jerison Michael J. McDonald Alex N Nguyen Ba Gregory I. Lang David Botstein Ivana Cvijović Angela M Phillips Aleksandra Walczak Thomas Dupic Joshua B. Plotkin Katherine R Lawrence Artur Rego-Costa Daniel Weissman Katya Kosheleva