Roman Yelensky
机构: CTO, Gritstone Oncology
每年引用次数
引用次数
引用: 20,408
H-指数: 61
I10-指数 : 77
出版物: 105
TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics
Jennifer J. Wheler , Filip Janku , Aung Naing , Yali Li
Molecular Cancer Therapeutics 15 ( 10) 2475 -2485
38
2016
Evaluation of 122 advanced-stage cutaneous squamous cell carcinomas by comprehensive genomic profiling opens the door for new routes to targeted therapies.
Rami N. Al-Rohil , Ashley J. Tarasen , J. Andrew Carlson , Kai Wang
Cancer 122 ( 2) 249 -257
40
2016
Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.
Jeffrey S. Ross , Kai Wang , Depinder Khaira , Siraj M. Ali
Cancer 122 ( 5) 702 -711
55
2016
Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti-HER2 targeted therapies.
Jeffrey S. Ross , Laurie M. Gay , Kai Wang , Siraj M. Ali
Cancer 122 ( 17) 2654 -2662
69
2016
Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer
Elizabeth R Plimack , Roland L Dunbrack , Timothy A Brennan , Mark D Andrake
European Urology 68 ( 6) 959 -967
251
2015
Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling
Sumanta K. Pal , Toni K. Choueiri , Kai Wang , Depinder Khaira
European Urology 70 ( 3) 516 -521
46
2016
Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes.
Lisa Giulino-Roth , Kai Wang , Theresa Y. MacDonald , Susan Mathew
Blood 120 ( 26) 5181 -5184
75
2012
Next generation sequencing of exceptional responders with BRAF-mutant melanoma: implications for sensitivity and resistance.
Jennifer Wheler , Roman Yelensky , Gerald Falchook , Kevin B Kim
BMC Cancer 15 ( 1) 61 -61
17
2015
Multiple gene aberrations and breast cancer: lessons from super-responders
Jennifer J. Wheler , Johnique T. Atkins , Filip Janku , Stacy L. Moulder
BMC Cancer 15 ( 1) 442 -442
8
2015
Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting
Brian A. Dougherty , Zhongwu Lai , Darren R. Hodgson , Maria C.M. Orr
Oncotarget 8 ( 27) 43653 -43661
49
2017
Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines
Edwin Choy , Roman Yelensky , Sasha Bonakdar , Robert M. Plenge
PLoS Genetics 4 ( 11) e1000287
198
2008
Use of the FoundationOne next-generation sequencing (NGS) assay to detect actionable alterations leading to clinical benefit of targeted therapies for relapsed and refractory breast cancer.
Jeffrey S. Ross , Massimo Cristofanilli , Sean Downing , Roman Yelensky
Journal of Clinical Oncology 31 1009 -1009
2
2013
Use of next-generation sequencing (NGS) to identify actionable genomic alterations (GA) in diverse solid tumor types: The Foundation Medicine (FMI) experience with 2,200+ clinical samples.
Vincent A. Miller , Jeffrey S. Ross , Kai Wang , Siraj M. Ali
Journal of Clinical Oncology 31 ( 15_suppl) 11020 -11020
4
2013
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
Jie He , Omar Abdel-Wahab , Michelle K. Nahas , Kai Wang
Blood 127 ( 24) 3004 -3014
145
2016
Efficiency and power in genetic association studies
Paul I W de Bakker , Roman Yelensky , Itsik Pe'er , Stacey B Gabriel
Nature Genetics 37 ( 11) 1217 -1223
1,603
2005
Evaluating and improving power in whole-genome association studies using fixed marker sets.
Itsik Pe'er , Paul I W de Bakker , Julian Maller , Roman Yelensky
Nature Genetics 38 ( 6) 663 -667
294
2006
Transferability of tag SNPs in genetic association studies in multiple populations
Johannah Butler , Stanton Young , Robert C Onofrio , Helen N Lyon
Nature Genetics 38 ( 11) 1298 -1303
263
2006
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
Doron Lipson , Marzia Capelletti , Roman Yelensky , Geoff Otto
Nature Medicine 18 ( 3) 382 -384
964
2012
A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: implications for clinical practice.
Neil Vasan , Roman Yelensky , Kai Wang , Stacy Moulder
Oncologist 19 ( 5) 453 -458
45
2014
New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing
Jeffrey S. Ross , Kai Wang , Laurie Gay , Rami Al‐Rohil
Oncologist 19 ( 3) 235 -242
428
2014