Thijn Brummelkamp
机构: Groupleader, Netherlands Cancer Institute
每年引用次数
引用次数
引用: 34,059
H-指数: 69
I10-指数 : 99
出版物: 160
A functionally distinct member of the DP family of E2F subunits.
A Milton , K Luoto , L Ingram , S Munro
Oncogene 25 ( 22) 3212 -3218
25
2006
Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.
T.R. BRUMMELKAMP , K. BERNS , E.M. HIJMANS , J. MULLENDERS
Cold Spring Harbor Symposia on Quantitative Biology 69 439 -446
16
2004
Yap1 acts downstream of α-catenin to control epidermal proliferation
Karin Schlegelmilch , Morvarid Mohseni , Oktay Kirak , Jan Pruszak
Cell 144 ( 5) 782 -795
1,016
2011
Inhibition of ATPIF1 Ameliorates Severe Mitochondrial Respiratory Chain Dysfunction in Mammalian Cells
Walter W. Chen , Kıvanç Birsoy , Maria M. Mihaylova , Harriet Snitkin
Cell Reports 7 ( 1) 27 -34
40
2014
Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.
Moniek Riemersma , D. Sean Froese , Walinka van Tol , Udo F. Engelke
Chemistry & Biology 22 ( 12) 1643 -1652
73
2015
An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis
H.M. Oosterkamp , H. Neering , S.M.B. Nijman , A.M.G. Dirac
British Journal of Dermatology 155 ( 1) 182 -185
43
2006
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
R. van der Kant , A. Fish , L. Janssen , H. Janssen
Journal of Cell Science 126 ( 15) 3462 -3474
133
2013
A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint
Thijn R. Brummelkamp , Stephen J. Smerdon , Alexandra Kate Gardino , Marcel A. T. M. van Vugt
PLoS
2010
Pla2g16 as a target for antiviral compounds
Thijn R. Brummelkamp , Jan E. Carette
2011
Ultra-deep genome mutagenesis in haploid human cells
Thijn R. Brummelkamp , Paul Saftig , John M. Dye , Jan E. Carette
Glycobiology
2016
Abstract A08: Genetic drug resistance screen identifies LZTR1 as regulator of RAS ubiquitination and signaling
Thijn R. Brummelkamp , Robert Kralovics , Marek Mlodzik , Giovanna M. Collu
Molecular Cancer Research 18
2020
Sphingolipid Biosynthesis Inhibition As A Host Strategy Against Diverse Pathogens
Sandeep Kumar , Jinmei Li , Jiwoong Park , Sydney K Hart
bioRxiv
2020
The Tubulin Detyrosination Cycle: Function and Enzymes
Joppe Nieuwenhuis , Thijn R. Brummelkamp
Trends in Cell Biology 29 ( 1) 80 -92
71
2019
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
Anne Margriet Heijink , Francien Talens , Lucas T. Jae , Stephanie E. van Gijn
Nature Communications 10 ( 1) 100 -100
2019
Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.
Athanassios Adamopoulos , Lisa Landskron , Tatjana Heidebrecht , Foteini Tsakou
Nature Structural & Molecular Biology 26 ( 7) 567 -570
14
2019
Vasohibins encode tubulin detyrosinating activity
Joppe Nieuwenhuis , Athanassios Adamopoulos , Onno B. Bleijerveld , Abdelghani Mazouzi
Science 358 ( 6369) 1453 -1456
175
2017
LZTR1 is a regulator of RAS ubiquitination and signaling
Johannes W. Bigenzahn , Giovanna M. Collu , Felix Kartnig , Melanie Pieraks
Science 362 ( 6419) 1171 -1177
119
2018
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
Thijn R. Brummelkamp , Sebastian M. B. Nijman , Annette M. G. Dirac , René Bernards
Nature 424 ( 6950) 797 -801
839
2003
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
Katrien Berns , E. Marielle Hijmans , Jasper Mullenders , Thijn R. Brummelkamp
Nature 428 ( 6981) 431 -437
1,430
2004
Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens
Jan E. Carette , Carla P. Guimaraes , Malini Varadarajan , Annie S. Park
Science 326 ( 5957) 1231 -1235
413
2009