Yap1 acts downstream of α-catenin to control epidermal proliferation

作者: Karin Schlegelmilch , Morvarid Mohseni , Oktay Kirak , Jan Pruszak , J. Renato Rodriguez

DOI: 10.1016/J.CELL.2011.02.031

关键词:

摘要: During development and regeneration, proliferation of tissue-specific stem cells is tightly controlled to produce organs of a predetermined size. The molecular determinants of this …

参考文章(59)
Kieran Harvey, Nicolas Tapon, The Salvador–Warts–Hippo pathway — an emerging tumour-suppressor network Nature Reviews Cancer. ,vol. 7, pp. 182- 191 ,(2007) , 10.1038/NRC2070
Tian Xu, R. A. Stewart, Wan Yu, Waiyi Wang, Sheng Zhang, Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase Development. ,vol. 121, pp. 1053- 1063 ,(1995) , 10.1242/DEV.121.4.1053
Dawang Zhou, Claudius Conrad, Fan Xia, Ji-Sun Park, Bernhard Payer, Yi Yin, Gregory Y. Lauwers, Wolfgang Thasler, Jeannie T. Lee, Joseph Avruch, Nabeel Bardeesy, Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene Cancer Cell. ,vol. 16, pp. 425- 438 ,(2009) , 10.1016/J.CCR.2009.09.026
Jacqueline M. Benjamin, W. James Nelson, Bench to Bedside and Back Again: Molecular Mechanisms of α-Catenin Function and Roles in Tumorigenesis Seminars in Cancer Biology. ,vol. 18, pp. 53- 64 ,(2008) , 10.1016/J.SEMCANCER.2007.08.003
Tsutomu Oka, Virginia Mazack, Marius Sudol, Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). Journal of Biological Chemistry. ,vol. 283, pp. 27534- 27546 ,(2008) , 10.1074/JBC.M804380200
Gusztav Belteki, Jody Haigh, Nikolett Kabacs, Katharina Haigh, Karen Sison, Frank Costantini, Jeff Whitsett, Susan E Quaggin, Andras Nagy, Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction Nucleic Acids Research. ,vol. 33, pp. 2765- 2765 ,(2005) , 10.1093/NAR/GNI051
Shian Wu, Yi Liu, Yonggang Zheng, Jixin Dong, Duojia Pan, The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway Developmental Cell. ,vol. 14, pp. 388- 398 ,(2008) , 10.1016/J.DEVCEL.2008.01.007
Bruce J Herron, Rebecca A Liddell, April Parker, Sarah Grant, Jennifer Kinne, Jill K Fisher, Linda D Siracusa, A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice Nature Genetics. ,vol. 37, pp. 1210- 1212 ,(2005) , 10.1038/NG1652
Paulo S. Ribeiro, Filipe Josué, Alexander Wepf, Michael C. Wehr, Oliver Rinner, Gavin Kelly, Nicolas Tapon, Matthias Gstaiger, Combined Functional Genomic and Proteomic Approaches Identify a PP2A Complex as a Negative Regulator of Hippo Signaling Molecular Cell. ,vol. 39, pp. 521- 534 ,(2010) , 10.1016/J.MOLCEL.2010.08.002
H. Zhang, H. A. Pasolli, E. Fuchs, Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 2270- 2275 ,(2011) , 10.1073/PNAS.1019603108