Phase 1 clinical trial of trametinib and ponatinib in patients with NSCLC harboring KRAS mutations

Kathryn C Arbour , Eusebio Manchado , Matthew J Bott , Linda Ahn
JTO Clinical and Research Reports 3 ( 1) 100256 -100256

10
2022
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma

Zhuxuan Li , Xueqian Zhuang , Chun-Hao Pan , Yan Yan
Cancer Discovery 14 ( 2) 308 -325

4
2024
Targeted therapy-induced senescence enhances immune surveillance of KRAS mutant lung cancers

Marcus Ruscetti , Josef Leibold , Matthew J Bott , Mario Shields
Cancer Research 78 ( 10 Sup)

2018
Design and Biochemical Characterization of Peptidic Inhibitors of the Myb/p300 Interaction

Matthew Jones , Philipp Grosche , Andreas Floersheimer , Jérome André
Biochemistry 62 ( 7) 1321 -1329

4
2023
The regulation by kinases of the expression of human major histocompatibility class I molecules

Elliott J Brea , Claire Oh , Eusebio Manchado , Ron Gejman
Cancer Research 76 ( 14_Supplement) 4899 -4899

2016
INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas

Ahmed MO Elbatsh , Ali Amin-Mansour , Anne Haberkorn , Claudia Textor
Nature cancer 1 -19

2024
Correction: Corrigendum: In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

Danilo Maddalo , Eusebio Manchado , Carla P Concepcion , Ciro Bonetti
Nature 524 ( 7566) 502 -502

7
2015
Promoter‐Driven Overexpression in Chromobacterium Vaccinii Facilitates Access to FR900359 and Yields Novel Low Abundance Analogs

Dominik Pistorius , Kathrin Buntin , Eric Weber , Etienne Richard
Chemistry–A European Journal 28 ( 8) e202103888 -e202103888

7
2022
SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS-mutant tumors treated with MEK inhibitors.

Hengyu Lu , Chen Liu , Roberto Velazquez , Hongyun Wang
MOLECULAR CANCER RESEARCH 18 ( 5) 52 -52

1
2020
Abstract A44: SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS-mutant tumors treated with MEK inhibitors

Hengyu Lu , Chen Liu , Roberto Velazquez , Hongyun Wang
Molecular Cancer Research 18 ( 5_Supplement) A44 -A44

2020
Treatment of tumors expressing mutant p53

Eusebio Manchado , Susann Weissmueller , Scott W Lowe , Michael Saborowski

2017
Killing cells by targeting mitosis

E Manchado , M Guillamot , M Malumbres
Cell Death & Differentiation 19 ( 3) 369 -377

173
2012