Abstract SY24-01: A SAGA of GCN5 and USP22 in stem cells and cancer
Sharon Y. R. Dent , Boyko Atanassov , Calley Hirsch , Evangelia Koutelou
Cancer Research 74
2014
A SAGA of GCN5 and USP22 in stem cells and cancer
Sharon YR Dent , Boyko Atanassov , Calley Hirsch , Evangelia Koutelou
CANCER RESEARCH 74 ( 19)
2014
Domain-Focused CRISPR-Cas9 Screen Identifies Hri Kinase As a Regulator of Fetal Hemoglobin in Adult Human Erythroid Cells
Gerd A. Blobel , Gerd A. Blobel , Laavanya Sankaranarayanan , Belinda Giardine
Blood 130 536 -536
2017
Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein Spop As a Novel Repressor of Fetal Hemoglobin
Xianjiang Lan , Eugene Khandros , Jeremy D. Grevet , Scott A. Peslak
Blood 132 414 -414
2
2018
Heme-Regulated Inhibitor (HRI) Loss and Pharmacologic Treatments Cooperate to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation
Scott A. Peslak , Jeremy D. Grevet , Xianjiang Lan , Osheiza Abdulmalik
Blood 132 721 -721
2018
Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.
Jeremy D. Grevet , Xianjiang Lan , Nicole Hamagami , Christopher R. Edwards
Science 361 ( 6399) 285 -290
124
2018
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
Xianjiang Lan , Eugene Khandros , Peng Huang , Scott A. Peslak
Blood Advances 3 ( 10) 1586 -1597
10
2019
HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation.
Scott A. Peslak , Eugene Khandros , Peng Huang , Xianjiang Lan
Blood Advances 4 ( 18) 4560 -4572
2
2020
The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
Peng Huang , Scott A. Peslak , Xianjiang Lan , Eugene Khandros
Blood 135 ( 24) 2121 -2132
35
2020
ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth
Boyko S. Atanassov , Ryan D. Mohan , Xianjiang Lan , Xianghong Kuang
Molecular Cell 62 ( 4) 558 -571
58
2016
Comparative analysis of duplicated sox21 genes in zebrafish.
Xianjiang Lan , Lu Wen , Kui Li , Xiaojun Liu
Development Growth & Differentiation 53 ( 3) 347 -356
12
2011
USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B
Xianjiang Lan , Boyko S. Atanassov , Wenqian Li , Ying Zhang
Cell Reports 17 ( 9) 2382 -2393
29
2016
Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing
Peng Huang , Scott A. Peslak , Xianjiang Lan , Eugene Khandros
Blood 134 814 -814
2019
Interrogating RNA Binding Proteins as Novel Regulators of Fetal Hemoglobin Expression
Aoi Wakabayashi , Jeremy D. Grevet , Xianjiang Lan , Malini Sharma
Blood 134 966 -966
2019
Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation
Scott A. Peslak , Xianjiang Lan , Eugene Khandros , Peng Huang
Blood 134 3557 -3557
2019
Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module
Xianjiang Lan , Evangelia Koutelou , Andria C. Schibler , Yi Chun Chen
Molecular and Cellular Biology 35 ( 10) 1777 -1787
23
2015
Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module.
Wenqian Li , Boyko S. Atanassov , Xianjiang Lan , Ryan D. Mohan
Molecular and Cellular Biology 36 ( 22) 2855 -2866
11
2016
Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410--DNA interaction using small angle X-ray scattering
Gundeep Kaur , Ren Ren , Michal Hammel , John R Horton
Nucleic acids research 51 ( 4) 1674 -1686
2023
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
Peng Huang , Scott A Peslak , Ren Ren , Eugene Khandros
Nature genetics 54 ( 9) 1417 -1426
3
2022
ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression
Xianjiang Lan , Ren Ren , Ruopeng Feng , Lana C Ly
Molecular cell 81 ( 2) 239 -254. e8
60
2021