引用次数
引用: 1,788
H-指数: 20
I10-指数 : 22
出版物: 32
LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma
Wenjin Liu , Kimberly B. Monahan , Adam D. Pfefferle , Takeshi Shimamura
Cancer Cell 21 ( 6) 751 -764
91
2012
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies
A. B. Hanker , A. D. Pfefferle , J. M. Balko , M. G. Kuba
Proceedings of the National Academy of Sciences of the United States of America 110 ( 35) 14372 -14377
119
2013
c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
R Nair , DL Roden , WS Teo , A McFarland
Oncogene
115
2013
A Pipeline to Determine RT-QPCR Control Genes for Evolutionary Studies: Application to Primate Gene Expression across Multiple Tissues
Olivier Fedrigo , Lisa R. Warner , Adam D. Pfefferle , Courtney C. Babbitt
PLOS ONE 5 ( 9) 1 -7
27
2010
Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (NF1) as a Breast Cancer Driver
Marsha D. Wallace , Adam D. Pfefferle , Lishuang Shen , Adrian J. McNairn
Genetics 192 ( 2) 385 -396
50
2012
Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis
J. Chuck Harrell , Adam D. Pfefferle , Nicole Zalles , Aleix Prat
Clinical & Experimental Metastasis 31 ( 1) 33 -45
37
2014
Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes
Jerry Usary , David Brian Darr , Adam D. Pfefferle , Charles M. Perou
Current protocols in pharmacology 72 ( 1)
35
2016
A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer
Daniel P. Hollern , Cristina M. Contreras , Stephanie Dance-Barnes , Grace O. Silva
Breast Cancer Research and Treatment 174 ( 1) 143 -155
4
2019
Comparative expression analysis of the phosphocreatine circuit in extant primates: Implications for human brain evolution
Adam D. Pfefferle , Lisa R. Warner , Catrina W. Wang , William J. Nielsen
Journal of Human Evolution 60 ( 2) 205 -212
45
2011
Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models
Patrick J. Roberts , Jerry E. Usary , David B. Darr , Patrick M. Dillon
Clinical Cancer Research 18 ( 19) 5290 -5303
110
2012
Both noncoding and protein-coding RNAs contribute to gene expression evolution in the primate brain.
Courtney C. Babbitt , Olivier Fedrigo , Adam D. Pfefferle , Alan P. Boyle
Genome Biology and Evolution 2 ( 1) 67 -79
97
2010
Oncogenic PI3K mutations lead to NF-κB-dependent cytokine expression following growth factor deprivation.
Jessica E. Hutti , Adam D. Pfefferle , Sean C. Russell , Mayukh Sircar
Cancer Research 72 ( 13) 3260 -3269
56
2012
Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression or signaling
Christian D. Young , Adam D. Pfefferle , Philip Owens , María G. Kuba
Cancer Research 73 ( 13) 4075 -4085
19
2013
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Adam D. Pfefferle , Yash N. Agrawal , Daniel C. Koboldt , Krishna L. Kanchi
Disease Models & Mechanisms 9 ( 7) 749 -757
16
2016
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Adam D. Pfefferle , David B. Darr , Benjamin C. Calhoun , Kevin R. Mott
Disease Models & Mechanisms 12 ( 7)
2
2019
c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.
Michael A. Cantrell , Nancy D. Ebelt , Adam D. Pfefferle , Charles M. Perou
Oncotarget 6 ( 14) 11863 -11881
4
2015
Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy
Adam D. Pfefferle , Benjamin T. Spike , Geoff M. Wahl , Charles M. Perou
Breast Cancer Research and Treatment 149 ( 2) 425 -437
24
2015
A Potential Role for Glucose Transporters in the Evolution of Human Brain Size
Olivier Fedrigo , Adam D. Pfefferle , Courtney C. Babbitt , Ralph Haygood
Brain Behavior and Evolution 78 ( 4) 315 -326
23
2011
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Adam D Pfefferle , Jason I Herschkowitz , Jerry Usary , Joshua Harrell
Genome Biology 14 ( 11) 1 -16
203
2013
Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells
Patrick D Rädler , Barbara L Wehde , Aleata A Triplett , Hridaya Shrestha
Nature Communications 12 ( 1) 3742
18
2021