p53 mutant mice that display early ageing-associated phenotypes

Stuart D. Tyner , Sundaresan Venkatachalam , Jene Choi , Stephen Jones
Nature 415 ( 6867) 45 -53

1,202
2002
The Integrin-linked Kinase Regulates the Cyclin D1 Gene through Glycogen Synthase Kinase 3β and cAMP-responsive Element-binding Protein-dependent Pathways

Mark D'Amico , James Hulit , Derek F. Amanatullah , Brian T. Zafonte
Journal of Biological Chemistry 275 ( 42) 32649 -32657

231
2000
Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.

George W. Hinkal , Catherine E. Gatza , Neha Parikh , Lawrence A. Donehower
Mechanisms of Ageing and Development 130 ( 4) 262 -271

36
2009
55K isoform of CDK9 associates with Ku70 and is involved in DNA repair.

Hongbing Liu , Christine H. Herrmann , Karen Chiang , Tzu-Ling Sung
Biochemical and Biophysical Research Communications 397 ( 2) 245 -250

25
2010
Dual Roles for the Phosphatase PPM1D in Regulating Progesterone Receptor Function

David A. Proia , Bonnie W. Nannenga , Lawrence A. Donehower , Nancy L. Weigel
Journal of Biological Chemistry 281 ( 11) 7089 -7101

28
2006
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

Christopher J. Kemp , Lawrence A. Donehower , Allan Bradley , Allan Balmain
Cell 74 ( 5) 813 -822

430
1993
Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Bernard Leroy , Mandy L. Ballinger , Fanny Baran-Marszak , Gareth L. Bond
Cancer Research 77 ( 6) 1250 -1260

69
2017
Altered mammary gland development in the p53+/m mouse, a model of accelerated aging

Catherine E. Gatza , Melissa Dumble , Frances Kittrell , David G. Edwards
Developmental Biology 313 ( 1) 130 -141

24
2008
A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice.

Michele Harvey , Hannes Vogel , Danna Morris , Allan Bradley
Nature Genetics 9 ( 3) 305 -311

209
1995
Cancer Prevention Studies in p53-Deficient Mice:

Stephen D. Hursting , Susan N. Perkins , Lawrence A. Donehower , Barbara J. Davis
Toxicologic Pathology 29 ( 1) 137 -141

18
2001
LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro

J. Jacob Wamsley , Natalia Issaeva , Hanbing An , Xinyuan Lu
Cell Cycle 16 ( 2) 213 -223

8
2017
Identification of Novel Amplification Gene Targets in Mouse and Human Breast Cancer at a Syntenic Cluster Mapping to Mouse ch8A1 and Human ch13q34

Martin C. Abba , Victoria T. Fabris , Yuhui Hu , Frances S. Kittrell
Cancer Research 67 ( 9) 4104 -4112

46
2007
Analysis of Human Immunodeficiency Virus Type 1 Integrase Mutants

M.Ali Ansari-Lari , Lawrence A. Donehower , Richard A. Gibbs
Virology 211 ( 1) 332 -335

72
1995
Retroviral vector-mediated transduction of K-ras antisense RNA into human lung cancer cells inhibits expression of the malignant phenotype.

Yujiao Zhang , Tapas Mukhopadhyay , Lawrence A. Donehower , Renee N. Georges
Human Gene Therapy 4 ( 4) 451 -460

167
1993
Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice

Neha Parikh , Ryan L. Shuck , Mihai Gagea , Lanlan Shen
Aging Cell 17 ( 1) e12691

17
2018
Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Zhongqi Ge , Jake S Leighton , Yumeng Wang , Xinxin Peng
Cell Reports 23 ( 1) 213

84
2018
The utility of genetically altered mouse models for cancer research.

Lawrence A. Donehower , John E. French , Stephen D. Hursting
Mutation Research 576 ( 1) 1 -3

5
2005
Probing p53 biological functions through the use of genetically engineered mouse models.

Laura D. Attardi , Lawrence A. Donehower
Mutation Research 576 ( 1) 4 -21

73
2005