Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease

Hyun-Sik Yang , Ling Teng , Daniel Kang , Vilas Menon
Nature Communications 14 ( 1) 7659 -7659

1
2023
Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21. 1 Distal and 15q11. 2 BP1-BP2 Deletion Carriers

Rune Boen , Tobias Kaufmann , Dennis Van der Meer , Oleksandr Frei
Biological psychiatry 95 ( 2) 147 -160

2
2024
High-effect gene-coding variants impact cognition, mental well-being, and neighborhood safety substrates in brain morphology

Jakub Kopal , Guillaume Huguet , Justin Marotta , Shambhavi Aggarwal
medRxiv 2024.05. 21.24307729 -2024.05. 21.24307729

2024
Principles and methods for transferring polygenic risk scores across global populations

Linda Kachuri , Nilanjan Chatterjee , Jibril Hirbo , Daniel J Schaid
Nature Reviews Genetics 25 ( 1) 8 -25

35
2024
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations

Niall J Lennon , Leah C Kottyan , Christopher Kachulis , Noura S Abul-Husn
Nature Medicine 1 -8

13
2024
Polygenic Risk for Type 2 Diabetes in African Americans

Marguerite R Irvin , Tian Ge , Amit Patki , Vinodh Srinivasasainagendra
Diabetes db230232 -db230232

2024
Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression

Ruoyu Tian , Tian Ge , Hyeokmoon Kweon , Daniel B Rocha
Nature Communications 15 ( 1) 1755 -1755

1
2024
Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits

JooEun Kang , Victor M Castro , Michael Ripperger , Sanan Venkatesh
American Journal of Psychiatry appi. ajp. 20230247 -appi. ajp. 20230247

2024
Identifying Nootropic Drug Targets via Large-Scale Cognitive GWAS and Transcriptomics

Max Lam , Chen Chia-Yen , Xia Yan , W David Hill
Biological Psychiatry 87 ( 9)

9
2020
The molecular genetic landscape of human brain size variation

Jakob Seidlitz , Travis T Mallard , Jacob W Vogel , Younga H Lee
Cell Reports 42 ( 11)

2
2023
Invariance principles allowing of non-Lyapunov functions for estimating attractor of discrete dynamical systems

Tian Ge , Wei Lin , Jianfeng Feng
IEEE Transactions on Automatic Control 57 ( 2) 500 -505

9
2011
Exploration of Alzheimer’s Disease MRI Biomarkers Using APOE4 Carrier Status in the UK Biobank

Jingnan Du , Zhaowen Liu , Lindsay C Hanford , Kevin M Anderson
medRxiv 2021.09. 09.21263324 -2021.09. 09.21263324

1
2021
1
2024
Age differences in the functional architecture of the human brain

Roni Setton , Laetitia Mwilambwe-Tshilobo , Manesh Girn , Amber W Lockrow
Cerebral Cortex 33 ( 1) 114 -134

56
2023
Improving the computation efficiency of polygenic risk score modeling: faster in Julia

Annika Faucon , Julian Samaroo , Tian Ge , Lea K Davis
Life Science Alliance 5 ( 12)

2022
Use of the PsycheMERGE network to investigate the association between depression polygenic scores and white blood cell count

Julia M Sealock , Younga H Lee , Arden Moscati , Sanan Venkatesh
JAMA psychiatry 78 ( 12) 1365 -1374

29
2021
Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis

Andrew D Grotzinger , Travis T Mallard , Zhaowen Liu , Jakob Seidlitz
Nature Communications 14 ( 1) 946 -946

15
2023
Impact of selection bias on polygenic risk score estimates in healthcare settings

Younga Heather Lee , Tanayott Thaweethai , Yi-Han Sheu , Yen-Chen Anne Feng
Psychological Medicine 53 ( 15) 7435 -7445

7
2023
Transcriptome-wide structural equation modeling of 13 major psychiatric disorders for cross-disorder risk and drug repurposing

Andrew D Grotzinger , Kritika Singh , Tyne W Miller-Fleming , Max Lam
JAMA psychiatry 80 ( 8) 811 -821

6
2023
Characterizing the phenotypic and genetic structure of psychopathology in UK Biobank

Camille M Williams , Hugo Peyre , Tobias Wolfram , Younga H Lee
medRxiv

2
2023