PO-092 Inhibition of the mTORC1-pathway can feedback-activate H-RAS or K-RAS

IM Posada , B Lectez , F Siddiqui , C Oetken-Lindholm
ESMO Open 3

2018
Serum lipidomic profiling identifies biomarkers associated with progression to type 2 diabetes in the METSIM study

L Yetukuri , H Cederberg , M Sysi-Aho , T Hyotylainen
Diabetologia 56 S60 -S60

1
2013
Rasvasolujen solukalvo mukautuu ylimääräiseen rasvaan

Laxman Yetukuri , Sergio Rodriguez-Cuenca , Anna-Liisa Ruskeepää , Antonio Vidal-Puig
Duodecim 127 ( 14) 1493

2011
Informatics strategies for phenotype characterization using lipid pathways

Mikko Katajamaa , Laxman Yetukuri , Tuulikki Seppänen-Laakso , Gema Medina-Gomez
intelligent systems in molecular biology

2007
Regulation of lipid metabolism in breast cancer

Marko Sysi-Aho , Laxman Yetukuri , Mika Hilvo , Tuulikki Seppänen-Laakso
Metabolomics 2010: Breakthroughs in plant, microbial and human biology, clinical and nutritional research, and biomarker discovery

2010
Informatics and computational strategies for the study of lipids

Laxman Yetukuri , Kim Ekroos , Antonio Vidal-Puig , Matej Orešič
Molecular BioSystems 4 ( 2) 121 -127

170
2008
Lipidome as a predictive tool in progression to type 2 diabetes in Finnish men

Tommi Suvitaival , Isabel Bondia-Pons , Laxman Yetukuri , Päivi Pöhö
Metabolism-clinical and Experimental 78 1 -12

53
2018
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1

Otto Kauko , Susumu Y. Imanishi , Evgeny Kulesskiy , Laxman Yetukuri
Journal of Biological Chemistry 295 ( 13) 4194 -4211

38
2020
Genomic, Transcriptomic, and Lipidomic Profiling Highlights the Role of Inflammation in Individuals With Low High-density Lipoprotein Cholesterol

Pirkka-Pekka Laurila , Ida Surakka , Antti-Pekka Sarin , Laxman Yetukuri
Arteriosclerosis, Thrombosis, and Vascular Biology 33 ( 4) 847 -857

38
2013
High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy

Laxman Yetukuri , Ilkka Huopaniemi , Artturi Koivuniemi , Marianna Maranghi
PLoS ONE 6 ( 8) e23589 -12

44
2011
Algorithms and tools for the preprocessing of LC–MS metabolomics data

Sandra Castillo , Peddinti Gopalacharyulu , Laxman Yetukuri , Matej Orešič
Chemometrics and Intelligent Laboratory Systems 108 ( 1) 23 -32

199
2011
Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism--the GENOBIN study.

Ursula Schwab , Tuulikki Seppänen-Laakso , Laxman Yetukuri , Jyrki Ågren
PLOS ONE 3 ( 7)

73
2008
Association of Lipidome Remodeling in the Adipocyte Membrane with Acquired Obesity in Humans

Kirsi H. Pietiläinen , Tomasz Róg , Tuulikki Seppänen-Laakso , Sam Virtue
PLoS Biology 9 ( 6) e1000623

167
2011
Adipose Tissue Inflammation and Increased Ceramide Content Characterize Subjects With High Liver Fat Content Independent of Obesity

Maria Kolak , Jukka Westerbacka , Vidya R. Velagapudi , Dick Wågsäter
Diabetes 56 ( 8) 1960 -1968

359
2007
Control of MYC-dependent apoptotic threshold by a co-amplified ubiquitin E3 ligase UBR5

Xi Qiao , Ying Liu , Maria Llamazares Prada , Abhishekh Gupta
bioRxiv 515247

2019
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.

Matej Orešič , Satu Simell , Marko Sysi-Aho , Kirsti Näntö-Salonen
Journal of Experimental Medicine 205 ( 13) 2975 -2984

331
2008
Gut microbiota affects lens and retinal lipid composition.

Matej Orešič , Tuulikki Seppänen-Laakso , Laxman Yetukuri , Fredrik Bäckhed
Experimental Eye Research 89 ( 5) 604 -607

27
2009
Rapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner.

Itziar M.D. Posada , Benoit Lectez , Mukund Sharma , Christina Oetken-Lindholm
Oncotarget 8 ( 27) 44550 -44566

19
2017
Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer Progression

Mika Hilvo , Carsten Denkert , Laura Lehtinen , Berit Müller
Cancer Research 71 ( 9) 3236 -3245

508
2011