Susumu S. Kobayashi
机构: Beth Israel Deaconess Medical Center
每年引用次数
引用次数
引用: 18,081
H-指数: 51
I10-指数 : 85
出版物: 214
Predictive analysis of microenvironment impact on clinical outcomes to drug agents using simulation of myeloproliferative neoplasms.
Peter P. Sayeski , Shireen Vali , Ansu Kumar , Neeraj Singh
Journal of Clinical Oncology 32 7110 -7110
2014
Erlotinib-associated alopecia in a lung cancer patient.
Daniel B. Costa , Susumu Kobayashi , Susan T. Schumer
Journal of Thoracic Oncology 2 ( 12) 1136 -1138
6
2007
Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells
Matteo Forloni , Romi Gupta , Arvindhan Nagarajan , Li-Sha Sun
Cell Reports 16 ( 2) 457 -471
24
2016
Three-dimensional magnetic resonance microscopy of pulmonary solitary tumors in transgenic mice.
Shigeto Kubo , Elena Levantini , Susumu Kobayashi , Olivier Kocher
Magnetic Resonance in Medicine 56 ( 3) 698 -703
13
2006
Spliceosomal Disruption of the Non-Canonical SWI/SNF Chromatin Remodeling Complex in SF3B1 Mutant Leukemias
Daichi Inoue , Chew Guo-Liang , Bo Liu , Stanley C Lee
Blood 134 637 -637
1
2019
A Distal Single Nucleotide Polymorphism Disrupts Development-Dependent Long-Range Transcriptional Regulation of the PU.1 Gene through the Chromatin-Remodeling Protein SATB1 in Acute Myeloid Leukemia.
Ulrich Steidl , Christian Steidl , Alexander Ebralidze , Bjoern Chapuy
Blood 110 ( 11) 3175 -3175
2007
Differential Effects of Gefitinib and Cetuximab on Non–small-cell Lung Cancers Bearing Epidermal Growth Factor Receptor Mutations
Toru Mukohara , Jeffrey A. Engelman , Nasser H. Hanna , Beow Y. Yeap
Journal of the National Cancer Institute 97 ( 16) 1185 -1194
395
2005
Abstract LB-399: Chronic inhibition of mutant EGFR in NSCLC leads to EGFR TKI resistance by TGF-β1 mediated epithelial to mesenchymal transition
Takeshi Shimamura , Julian Carretero , Chunxiao Xu , Marzia Capelletti
Cancer Research 71
2011
Dysregulation Of Bcl2 Family Proteins Induced By JAK2V617F Mutation Contributes To The Abnormal Expansion Of Neoplastic Initiating Cells
Lorena Lobo Figueiredo-Pontes , Robert S Welner , Yuta Mishima , Mihoko Yamamoto
Blood 122 ( 21) 2852 -2852
2013
Sensitivity to EGFR inhibitors based on location of EGFR exon 20 insertion mutations within the tyrosine kinase domain of EGFR.
Daniel Botelho Costa , Hiroyuki Yasuda , Natasha J Sng , Wee-Lee Yeo
Journal of Clinical Oncology 30 7523 -7523
6
2012
EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications
Hiroyuki Yasuda , Susumu Kobayashi , Daniel B Costa
Lancet Oncology 13 ( 1)
540
2012
Alternative Splicing of APOBEC3D Generates Functional Diversity and Its Role As a DNA Mutator
Hisashi Takei , Masanori Fujii , Sohei Nakayama , Ikei Kobayashi
Blood 128 ( 22) 5107 -5107
2016
EGFR-A763_Y764insFQEA: A unique exon 20 insertion mutation that displays sensitivity to all classes of approved lung cancer EGFR tyrosine kinase inhibitors.
Carol Gergis , Deepa Rangachari , Masanori Fujii , Andreas Varkaris
Journal of Clinical Oncology 37
1
2019
Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells
Britta Will , Tanya Siddiqi , Meritxell Alberich Jordà , Takeshi Shimamura
Blood 115 ( 14) 2901 -2909
46
2010
Long read sequencing reveals a novel class of structural aberrations in cancers: identification and characterization of cancerous local amplifications
Yoshitaka Sakamoto , Liu Xu , Masahide Seki , Toshiyuki T. Yokoyama
bioRxiv 620047
6
2019
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
Hongbin Ji , Danan Li , Liang Chen , Takeshi Shimamura
Cancer Cell 9 ( 6) 485 -495
513
2006
BIM Mediates EGFR Tyrosine Kinase Inhibitor-Induced Apoptosis in Lung Cancers with Oncogenic EGFR Mutations
Daniel B Costa , Balázs Halmos , Amit Kumar , Susan T Schumer
PLOS Medicine 4 ( 10) 1669 -1680
545
2007
An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.
Susumu Kobayashi , Hongbin Ji , Yuki Yuza , Matthew Meyerson
Cancer Research 65 ( 16) 7096 -7101
310
2005
CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer–binding protein alpha
Carsten Müller-Tidow , Hubert Serve , Daniel G. Tenen , Steffen Koschmieder
Blood 110 ( 10) 3695 -3705
68
2007
Dual ALK and EGFR inhibition targets a mechanism of acquired resistance to the tyrosine kinase inhibitor crizotinib in ALK rearranged lung cancer.
Norihiro Yamaguchi , Antonio R. Lucena-Araujo , Sohei Nakayama , Lorena L. de Figueiredo-Pontes
Lung Cancer 83 ( 1) 37 -43
60
2014