Bruce L Levine
机构: Barbara and Edward Netter Professor in Cancer Gene Therapy, Department of Pathology and Laboratory
每年引用次数
引用次数
引用: 71,905
H-指数: 109
I10-指数 : 263
出版物: 575
Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Stephan A. Grupp , Eline Luning Prak , Jean Boyer , Kenyetta R. McDonald
Clinical Cancer Research 18 ( 24) 6732 -6741
46
2012
Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.
Andrew M. Stein , Stephan A. Grupp , John E. Levine , Theodore W. Laetsch
CPT: Pharmacometrics & Systems Pharmacology 8 ( 5) 285 -295
74
2019
T cell engineering as therapy for cancer and HIV: our synthetic future
Carl H. June , Bruce L. Levine
Philosophical Transactions of the Royal Society B 370 ( 1680) 20140374 -20140374
20
2015
Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T cell Therapy for Acute Lymphoblastic Leukemia
David T. Teachey , Simon F. Lacey , Pamela A. Shaw , J. Joseph Melenhorst
Cancer Discovery 6 ( 6) 664 -679
813
2016
Phase IIa Trial of Chimeric Antigen Receptor Modified T Cells Directed Against CD19 (CTL019) in Patients with Relapsed or Refractory CD19+ Lymphomas
Stephen J. Schuster , Jakub Svoboda , Sunita Dwivedy Nasta , David L. Porter
Blood 124 ( 21) 3087 -3087
14
2014
T Cells Engineered with a Chimeric Antigen Receptor (CAR) Targeting CD19 (CTL019) Have Long Term Persistence and Induce Durable Remissions in Children with Relapsed, Refractory ALL
Stephan A. Grupp , Shannon L Maude , Pamela Shaw , Richard Aplenc
Blood 124 ( 21) 380 -380
19
2014
Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia
David L. Porter , Bruce L. Levine , Michael Kalos , Adam Bagg
The New England Journal of Medicine 365 ( 8) 725 -733
4,024
2011
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia.
Stephan A. Grupp , Michael Kalos , David Barrett , Richard Aplenc
The New England Journal of Medicine 368 ( 16) 1509 -1518
3,625
2013
Gene Editing ofCCR5in Autologous CD4 T Cells of Persons Infected with HIV
Pablo Tebas , David Stein , Winson W. Tang , Ian Frank
New England Journal of Medicine 370 ( 10) 901 -910
1,555
2014
Chimeric antigen receptor T cells for sustained remissions in leukemia.
Shannon L Maude , Noelle Frey , Pamela A Shaw , Richard Aplenc
The New England Journal of Medicine 371 ( 16) 1507 -1517
4,951
2014
Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma
Alfred L. Garfall , Marcela V. Maus , Wei-Ting Hwang , Simon F. Lacey
The New England Journal of Medicine 373 ( 11) 1040 -1047
377
2015
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
Shannon L. Maude , Theodore W. Laetsch , Jochen Buechner , Susana Rives
The New England Journal of Medicine 378 ( 5) 439 -448
3,520
2018
Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas
Stephen J. Schuster , Jakub Svoboda , Elise A. Chong , Sunita D. Nasta
The New England Journal of Medicine 377 ( 26) 2545 -2554
1,392
2017
Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of Costimulated autologous T cells
Aaron P. Rapoport , Edward A. Stadtmauer , Nicole Aqui , Dan Vogl
Clinical Cancer Research 15 ( 13) 4499 -4507
79
2009
B cell maturation antigen–specific CAR T cells are clinically active in multiple myeloma
Adam D. Cohen , Alfred L. Garfall , Edward A. Stadtmauer , J. Joseph Melenhorst
Journal of Clinical Investigation 129 ( 6) 2210 -2221
482
2019
Adoptive Transfer of Autologous CD25-Depleted, CD3/CD28-Costimulated T Cells After Cyclophosphamide - Fludarabine Chemotherapy in Patients with Low-Grade Follicular Lymphoma: Long-Term Follow up
Stephen J. Schuster , Nicole A. Aqui , Benjamin Musher , Bruce L. Levine
Blood 120 ( 21) 1631 -1631
2012
CD19-Redirected Chimeric Antigen Receptor T (CART19) Cells Induce a Cytokine Release Syndrome (CRS) and Induction of Treatable Macrophage Activation Syndrome (MAS) That Can Be Managed by the IL-6 Antagonist Tocilizumab (toc).
Stephan A. Grupp , David L Porter , David T Teachey , David M. Barrett
Blood 120 ( 21) 2604 -2604
12
2012
Combination Immunotherapy After ASCT for Multiple Myeloma (MM) Using MAGE-A3/Poly-ICLC Immunizations Followed by Vaccine-Primed and Activated Autologous T-Cells
Aaron P. Rapoport , Nicole A. Aqui , Edward A. Stadtmauer , Ashraf Z. Badros
Blood 120 ( 21) 352 -352
4
2012
In vitro–expanded human CD4+CD25+ T-regulatory cells can markedly inhibit allogeneic dendritic cell–stimulated MLR cultures
Wayne R. Godfrey , Ying G. Ge , Darrin J. Spoden , Bruce L. Levine
Blood 104 ( 2) 453 -461
277
2004
L-Selectinhi but not the L-selectinlo CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
Patricia A. Taylor , Angela Panoskaltsis-Mortari , Jessica M. Swedin , Philip J. Lucas
Blood 104 ( 12) 3804 -3812
334
2004