引用次数
引用: 3,864
H-指数: 20
I10-指数 : 25
出版物: 53
Cell-programmed nutrient partitioning in the tumour microenvironment
W Kimryn Rathmell , W Kimryn Rathmell , Anna Chytil , Emily F Mason
Nature 593 ( 7858) 282 -288
298
2021
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1
Rodrigo Romero , Francisco J. Sánchez-Rivera , Peter M. K. Westcott , Kim L. Mercer
Nature Cancer 1 ( 9) 935 -935
2020
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1
Rodrigo Romero , Francisco J. Sánchez-Rivera , Peter M. K. Westcott , Kim L. Mercer
Nature Cancer 1 ( 6) 589 -602
35
2020
TOR complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites.
Françoise M. Roelants , Neha Chauhan , Alexander Muir , Jameson C. Davis
Molecular Biology of the Cell 29 ( 17) 2128 -2136
21
2018
Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
Mark R. Sullivan , Katherine R. Mattaini , Emily A. Dennstedt , Anna A. Nguyen
Cell Metabolism 29 ( 6) 1410
76
2019
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.
Mark R Sullivan , Laura V Danai , Caroline A Lewis , Sze Ham Chan
eLife 8
282
2019
TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids
Alexander Muir , Subramaniam Ramachandran , Françoise M Roelants , Garrett Timmons
eLife 3
108
2014
Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress
Alexander Muir , Françoise M Roelants , Garrett Timmons , Kristin L Leskoske
eLife 4
38
2015
Sphingolipid biosynthesis upregulation by TOR complex 2–Ypk1 signaling during yeast adaptive response to acetic acid stress
Joana F. Guerreiro , Alexander Muir , Subramaniam Ramachandran , Jeremy Thorner
Biochemical Journal 473 ( 23) 4311 -4325
39
2016
Altered exocrine function can drive adipose wasting in early pancreatic cancer.
Laura V. Danai , Ana Babic , Michael H. Rosenthal , Emily A. Dennstedt
Nature 558 ( 7711) 600 -604
63
2018
Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies.
Alexander Muir , Laura V. Danai , Matthew G. Vander Heiden
Disease Models & Mechanisms 11 ( 8)
65
2018
TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae
Françoise M. Roelants , Kristin L. Leskoske , Ross T. A. Pedersen , Alexander Muir
Molecular and Cellular Biology 37 ( 7)
34
2017
The nutrient environment affects therapy.
Alexander Muir , Matthew G. Vander Heiden
Science 360 ( 6392) 962 -963
59
2018
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer.
Volkan I Sayin , Sarah E LeBoeuf , Simranjit X Singh , Shawn M Davidson
eLife 6
151
2017
Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition.
Alexander Muir , Laura V Danai , Dan Y Gui , Chiara Y Waingarten
eLife 6
213
2017
Isolation and Quantification of Metabolite Levels in Murine Tumor Interstitial Fluid by LC/MS.
Mark Sullivan , Caroline Lewis , Alexander Muir
Bio-protocol 9 ( 22)
2019
Pancreatic tumors activate arginine biosynthesis to adapt to myeloid-driven amino acid stress
Juan J Apiz-Saab , Lindsey N Dzierozynski , Patrick B Jonker , Zhou Zhu
bioRxiv 2022 -06
1
2022
Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection
Mark R Sullivan , Kerry McGowen , Qiang Liu , Chidiebere Akusobi
Nature Microbiology 8 ( 3) 481 -497
2023
Cell envelope remodeling requires high concentrations of biotin during Mycobacterium abscessus model lung infection
Mark R Sullivan , Kerry McGowen , Qiang Liu , Chidiebere Akusobi
bioRxiv 2022 -07
2022
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 (vol 1, pg 589, 2020)
Rodrigo Romero , Francisco J Sanchez-Rivera , Peter MK Westcott , Kim L Mercer
NATURE CANCER 1 ( 9) 935 -935
2020
Caroline A. (Lewis) Chidley Jeremy W. THORNER PhD Mark R. Sullivan Thales Papagiannakopoulos Aaron M. Hosios Jared R. Mayers Elizaveta (Lisa) Freinkman Allison N. Lau Subramaniam Ramachandran David K Breslow Volkan Sayin Richard Possemato Rodrigo Romero Peggy Ping Hsu Isabel Sá-Correia Joana F Guerreiro tim levine Neha Chauhan