Mammalian eukaryotic initiation factor 2 kinases functionally substitute for GCN2 in the GCN4 translational control mechanism of yeast
TE Dever , JJ Chen , GN Barber , AM Cigan
Proc. Natl. Acad. Sci. USA 90 4616 -4620
29
1993
Mammalian eIf-2a-PKs functionally substitute for GCN2 and stimulate GCN4 translation in yeast
T Dever , JJ Chen , GN Barber , AM Cigan
Proc. Natl. Acad. Sci. USA 90 4616 -4620
9
1993
Autophosphorylations of heme-regulated eIF-2 alpha kinase at multiple sites are essential for its stability, activity and heme-response
BN Bauer , Y Chuu , JJ Chen
FASEB JOURNAL 13 ( 7) A1365 -A1365
1
1999
Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase
J. J. Chen , M. S. Throop , L. Gehrke , I. Kuo
Proceedings of the National Academy of Sciences of the United States of America 88 ( 17) 7729 -7733
166
1991
Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 alpha subunit kinase: homology to protein kinases.
J. J. Chen , J. K. Pal , R. Petryshyn , I. Kuo
Proceedings of the National Academy of Sciences of the United States of America 88 ( 2) 315 -319
49
1991
Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast.
T. E. Dever , J. J. Chen , G. N. Barber , A. M. Cigan
Proceedings of the National Academy of Sciences of the United States of America 90 ( 10) 4616 -4620
182
1993
Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells.
R. Petryshyn , J. J. Chen , I. M. London
Proceedings of the National Academy of Sciences of the United States of America 85 ( 5) 1427 -1431
59
1988
Recycling and phosphorylation of eukaryotic initiation factor 2 on 60S subunits of 80S initiation complexes and polysomes
K. V. Ramaiah , R. S. Dhindsa , J. J. Chen , I. M. London
Proceedings of the National Academy of Sciences of the United States of America 89 ( 24) 12063 -12067
25
1992
Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1
J. Chou , J. J. Chen , M. Gross , B. Roizman
Proceedings of the National Academy of Sciences of the United States of America 92 ( 23) 10516 -10520
268
1995
Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates.
R.L. Matts , Z Xu , J.K. Pal , J.J. Chen
Journal of Biological Chemistry 267 ( 25) 18160 -18167
63
1992
Regulation of heme-regulated eIF-2α kinase and its expression in erythroid cells
J.J. Chen , J.S. Crosby , I.M. London
Biochimie 76 ( 8) 761 -769
31
1994
Effects of hemin and porphyrin compounds on intersubunit disulfide formation of heme-regulated eIF-2 alpha kinase and the regulation of protein synthesis in reticulocyte lysates.
J.M. Yang , I.M. London , J.J. Chen
Journal of Biological Chemistry 267 ( 28) 20519 -20524
33
1992
The effects of N-ethylmaleimide on the phosphorylation and aggregation of insulin receptors in the isolated plasma membranes of 3T3-F442A adipocytes.
I M London , J J Chen , N S Kosower , R Petryshyn
Journal of Biological Chemistry 261 ( 2) 902 -908
15
1986
Inhibition of protein synthesis in insect cells by baculovirus-expressed heme-regulated eIF-2 alpha kinase.
P J Chefalo , J M Yang , K V Ramaiah , L Gehrke
Journal of Biological Chemistry 269 ( 41) 25788 -25794
23
1994
Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells.
J J Chen , I M London , R Petryshyn
Journal of Biological Chemistry 259 ( 23) 14736 -14742
69
1984
A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation.
Yi Liu , Michael J. Trnka , Shenheng Guan , Doyoung Kwon
Molecular & Cellular Proteomics 19 ( 12) 1968 -1986
2
2020
Transient inhibition of protein synthesis induces expression of proto‐oncogenes and stimulates resting cells to enter the cell cycle
I. B. Rosenwald , N. A. Setkov , V. N. Kazakov , J.-J. Chen
Cell Proliferation 28 ( 12) 631 -644
25
1995
Deficiency of heme-regulated eIF2α kinase decreases hepcidin expression and splenic iron in HFE−/− mice
S. Liu , R. N.V.S. Suragani , A. Han , W. Zhao
Haematologica 93 ( 5) 753 -756
15
2008
Effect of 5-phosphoribosyl-1-pyrophosphate on de novo pyrimidine biosynthesis in cultured ehrlich ascites cells made permeable with dextran sulfate 500.
J Chen , Mary Ellen Jones
2697 -2697
34
1979
Translational Regulation of Eukaryotic Protein Synthesis by Phosphorylation of eIF-2α
IRVING M LONDON , DANIEL H LEVIN , ROBERT L MATTS , N SHAUN B THOMAS
Academic Press 515 -543
1
1985