The impact and significance of CYP2E1 localization in butadiene-exposed mice

Gunnar Boysen , Jessica H. Hartman , Andres A. Caro , Grover P. Miller
Drug Metabolism Reviews 48

2016
Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data.

Volker M. Lauschke , Laura E. Russell , Jasleen Sodhi , Mehdi El Hassani
Drug Metabolism Reviews 1 -27

2021
Cooperative effects for CYP2E1 differ between styrene and its metabolites.

Jessica H. Hartman , Gunnar Boysen , Grover P. Miller
Xenobiotica 43 ( 9) 755 -764

8
2013
Predicting CYP2C19 catalytic parameters for enantioselective oxidations using artificial neural networks and a chirality code

Jessica H. Hartman , Steven D. Cothren , Sun-Ha Park , Chul-Ho Yun
Bioorganic & Medicinal Chemistry 21 ( 13) 3749 -3759

7
2013
Zebrafish have an ethanol-inducible hepatic 4-nitrophenol hydroxylase that is not CYP2E1-like.

Jessica H. Hartman , Jordan S. Kozal , Richard T. Di Giulio , Joel N. Meyer
Environmental Toxicology and Pharmacology 54 142 -145

1
2017
In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions.

Allison L. Phillips , Nicholas J. Herkert , Jake C. Ulrich , Jessica H. Hartman
Chemical Research in Toxicology 33 ( 6) 1428 -1441

1
2020
Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells.

April C.L. Bostian , Leena Maddukuri , Megan R. Reed , Tatsiana Savenka
Chemical Research in Toxicology 29 ( 1) 101 -108

12
2016
CYP2E1 hydroxylation of aniline involves negative cooperativity.

Jessica H. Hartman , Katie Knott , Grover P. Miller
Biochemical Pharmacology 87 ( 3) 523 -533

16
2014
Cooperativity in CYP2E1 metabolism of acetaminophen and styrene mixtures

Jessica H. Hartman , Lynda G. Letzig , Dean W. Roberts , Laura P. James
Biochemical Pharmacology 97 ( 3) 341 -349

12
2015
CYP2E1 metabolism of styrene involves allostery.

Jessica H. Hartman , Gunnar Boysen , Grover P. Miller
Drug Metabolism and Disposition 40 ( 10) 1976 -1983

19
2012
Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans.

Latasha L. Smith , Ian T. Ryde , Jessica H. Hartman , Riccardo F. Romersi
Neurotoxicology 74 209 -220

3
2019
Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity.

Jessica H. Hartman , Grover P. Miller , Gunnar Boysen
Toxicology 318 ( 1) 51 -58

7
2014
Subcellular localization of rat CYP2E1 impacts metabolic efficiency toward common substrates.

Jessica H. Hartman , H. Cass Martin , Andres A. Caro , Amy R. Pearce
Toxicology 338 47 -58

13
2015
1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.

Jessica H. Hartman , Grover P. Miller , Andres A. Caro , Stephanie D. Byrum
Toxicology 378 114 -124

20
2017
Novel isomeric metabolite profiles correlate with warfarin metabolism phenotype during maintenance dosing in a pilot study of 29 patients.

Dakota L. Pouncey , Jessica H. Hartman , Page C. Moore , David J. Dillinger
Blood Coagulation & Fibrinolysis 29 ( 7) 602 -612

2018
Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration.

Ricardo Laranjeiro , Girish Harinath , Jennifer E. Hewitt , Jessica H. Hartman
Proceedings of the National Academy of Sciences of the United States of America 116 ( 47) 23829 -23839

15
2019
Toxicological implications of mitochondrial localization of CYP2E1

Jessica H. Hartman , Grover P. Miller , Joel N. Meyer
Toxicology Research 6 ( 3) 273 -289

9
2017
Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics.

Jinxin Zhang , Jessica H. Hartman , Chuyi Chen , Shujie Yang
Lab on a Chip 20 ( 10) 1729 -1739

17
2020
Structural basis for cooperative binding of azoles to CYP2E1 as interpreted through guided molecular dynamics simulations

Joseph W. Levy , Jessica H. Hartman , Martin D. Perry , Grover P. Miller
Journal of Molecular Graphics and Modelling 56 43 -52

13
2015