Oncogenic fusion kinases in lung cancer

Aria Vaishnavi
University of Colorado Anschutz Medical Campus. Strauss Health Sciences Library

2017
Abstract A29: The CUTO panel of patient-derived NSCLC cell lines reveals unique molecular characteristics and responses to targeted therapies

Anh Tuan Le , Adriana Estrada-Bernal , Laura Schubert , Andrea Doak
Clinical Cancer Research 24

2018
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.

Doron Lipson , Philip J Stephens , Vince A Miller , Marileila Varella-Garcia
Nature Medicine 19 ( 11) 1469 -1472

402
2013
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

Gorjan Hrustanovic , Victor Olivas , Evangelos Pazarentzos , Asmin Tulpule
Nature Medicine 21 ( 9) 1038 -1047

257
2015
TRKing Down an Old Oncogene in a New Era of Targeted Therapy

Aria Vaishnavi , Anh T. Le , Robert C. Doebele
Cancer Discovery 5 ( 1) 25 -34

535
2015
An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101

Robert C. Doebele , Lara E. Davis , Aria Vaishnavi , Anh T. Le
Cancer Discovery 5 ( 10) 1049 -1057

227
2015
EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases.

Aria Vaishnavi , Laura Schubert , Uwe Rix , Lindsay A. Marek
Cancer Research 77 ( 13) 3551 -3563

40
2017
NTRK1 gene fusions as a novel oncogene target in lung cancer.

Robert Charles Doebele , Aria Vaishnavi , Marzia Capelletti , Anh T Le
Journal of Clinical Oncology 31 8023 -8023

17
2013
Analysis of NTRK1 gene fusion incidence in an unselected cohort of non-small cell lung cancer patients.

Robert Charles Doebele , Severine Kako , Anh T Le , Marcos da Costa Silva
Journal of Clinical Oncology 32 ( 15_suppl) 8048 -8048

2014
Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer.

Aria Vaishnavi , Michael T. Scherzer , Conan G. Kinsey , Gennie L. Parkman
Cell Reports 32 ( 5) 107994

1
2020
Resistance to ROS1 Inhibition Mediated by EGFR Pathway Activation in Non-Small Cell Lung Cancer

Kurtis D. Davies , Sakshi Mahale , David P. Astling , Dara L. Aisner
PLOS ONE 8 ( 12)

88
2013
Abstract B29: Oncogenic K-ras addiction in NSCLC switches PKCδ from a pro-apoptotic to a pro-survival signal

Angela M. Ohm , Aria Vaishnavi , Jennifer Symonds , Mary E. Reyland
Clinical Cancer Research 18

2012
Transposon mutagenesis reveals RBMS3 silencing as a promoter of malignant progression of BRAFV600E-driven lung tumorigenesis

Aria Vaishnavi , Joseph Juan , Maebh Jacob , Christopher Stehn
Cancer research 82 ( 22) 4261 -4273

1
2022
Transposon Mutagenesis Reveals RBMS3 as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

Aria Vaishnavi , Joseph Juan , Michael T Scherzer , J Edward VanVeen
bioRxiv 2022 -02

2022
BRAFV600E-mutant metastatic NSCLC: disease overview and treatment landscape

David Planchard , Rachel E Sanborn , Marcelo V Negrao , Aria Vaishnavi
NPJ Precision Oncology 8 ( 1) 90 -90

2024
Adaptive Survival Signaling in Oncogenic Fusion Kinase Addicted NSCLC

Aria Vaishnavi , Stephen B Keysar , Anh T Le , Dara L Aisner
JOURNAL OF THORACIC ONCOLOGY 10 ( 9) S214 -S214

1
2015
The CUTO panel of patient-derived NSCLC cell lines reveals unique molecular characteristics and responses to targeted therapies

Anh Tuan Le , Adriana Estrada-Bernal , Laura Schubert , Andrea Doak
CLINICAL CANCER RESEARCH 24 ( 17)

2018
EGFR is a conspiring kinase in gene fusion positive lung cancer

Aria Vaishnavi , Anh T Le , Stephen B Keysar , Christine M Lovly
Cancer Research 74 ( 19_Supplement) 5255 -5255

2014
Preclinical Modeling of Pathway-Targeted Therapy of Human Lung Cancer in the Mouse

Aria Vaishnavi , Conan G Kinsey , Martin McMahon
Cold Spring Harbor Perspectives in Medicine 14 ( 1) a041385 -a041385

1
2024
Combined TRKA and MEK1/2 Inhibition Forestalls the Onset of Acquired Resistance in a New Preclinical Model of NTRK1+ Pancreatic Cancer

Aria Vaishnavi , Michael T Scherzer , Conan Kinsey , Ignacio Garrido-Laguna
Cancer Research 80 ( 16_Supplement) 3769 -3769

2020