引用次数
引用: 5,856
H-指数: 42
I10-指数 : 65
出版物: 126
HETERONUCLEAR NMR AND PHOTOAFFINITY-LABELING STUDIES OF THE MUTT ENZYME AND ITS INTERACTION WITH SUBSTRATES
C Abeygunawardana , DJ Weber , AG Gittis , DN Frick
FASEB JOURNAL 9 ( 6) A1466 -A1466
2
1995
COMPLETE SEQUENCE-SPECIFIC NMR ASSIGNMENTS OF BACKBONE H-1, C-13, AND N-15 RESONANCES AND SOLUTION SECONDARY STRUCTURE OF THE MUT T ENZYME
DJ Weber , C Abeygunawardana , DN Frick , MJ Bessman
FASEB JOURNAL 7 ( 7) A1289 -A1289
2
1993
KINETIC AND MAGNETIC-RESONANCE STUDIES OF THE ROLE OF METALS IN THE MUT-T REACTION
DN Frick , DJ Weber , MJ Bessman , AS Mildvan
FASEB JOURNAL 7 ( 7) A1064 -A1064
1
1993
CHARACTERIZATION OF THE ORF17 PROTEIN FROM ESCHERICHIA-COLI
SF OHANDLEY , DN Frick , LC Bullions , AS Mildvan
FASEB JOURNAL 9 ( 6) A1299 -A1299
4
1995
THE MUT T FAMILY OF NUCLEOSIDE TRIPHOSPHATASES
DN Frick , LC Bullions , BD Townsend , MJ Bessman
FASEB JOURNAL 8 ( 7) A1278 -A1278
4
1994
Effect of substrate traps on hepatitis C virus NS3 helicase catalyzed DNA unwinding: Evidence for enzyme catalyzed strand exchange
Ryan S Rypma , AM Lam , DN Frick
Bacterial DNA, DNA Polymerase and DNA Helicases. New York: Nova Science Publishers, Inc 389 -407
3
2009
Defining the DNA binding site on hepatitis C virus NS3 helicase as a potential site for rational drug design [abstract 146]
D Keeney , AM Lam , F Jaffe , R Gallagher
Hepatology 36 203A -203A
1
2002
SPECIFICITY OF A SYMMETRIC BENZIMIDAZOLE HELICASE INHIBITOR
C Belon , YD High , T Lin , F Pauwels
JOURNAL OF INVESTIGATIVE MEDICINE 58 ( 4) 644 -644
2010
Site-directed mutagenesis reveals critical residues in the hepatitis C virus NS3 helicase
DN Frick , AM Lam , D Keeney , RS Rypma
FASEB JOURNAL 17 ( 4) A597 -A597
2003
Effects of his-tag fusion peptides on the helicase activity of hepatitis C virus NS3 protein
RS Rypma , AM Lam , DN Frick
FASEB JOURNAL 17 ( 4) A568 -A568
2003
A novel helicase template specificity is conserved among hepatitis C virus genotypes: Implications for drug design.
DN Frick , AM Lam
HEPATOLOGY 36 ( 4) 304A -304A
2002
Ribavirin-triphosphate fuels nucleic acid unwinding by the hepatitis C virus NS3 helicase.
AM Lam , DN Frick
HEPATOLOGY 36 ( 4) 383A -383A
2002
The carboxyl terminus of the HC-VNS5A protein and the 3'-UTR stabilize the expression of NS5B RNA-dependent RNA polymerase in Escherichia coli.
DN Frick
HEPATOLOGY 34 ( 4) 416A -416A
2001
The monomeric mutant of the gene 4 primase/helicase of bacteriophage T7 forms the stable lagging-strand complex.
M Kato , DN Frick , J Lee , CC Richardson
BIOPHYSICAL JOURNAL 80 ( 1) 476A -476A
2001
Mutagenesis and heteronuclear NMR studies of the role of Glu-57 in the mechanism of the mut T enzyme.
J Lin , C Abeygunawardana , DN Frick , MJ Bessman
BIOPHYSICAL JOURNAL 70 ( 2) SU163 -SU163
1996
Crystal Structure of the Primase Domain of the T7 Primase-Helicase
M Kato , DN Frick , CC Richardson , T Ellenberger
HCV helicase inhibitors and methods of use thereof
Jeffrey Aube , Brian Scott Jonathan Blagg , Kevin John Frankowski , David Norman Frick
2016
The catalytic core of the Escherichia coli MutT enzyme: Identification and characterization of a novel loop-helix-loop nucleotide phosphoanhydrase motif
David Norman Frick
The Johns Hopkins University
1995
HETERONUCLEAR NMR-STUDIES OF THE STRUCTURE OF THE MUTT ENZYME AND ITS INTERACTION WITH SUBSTRATE-ANALOGS
C ABEYGUANWARDANA , DJ WEBER , AG GITTIS , DN FRICK
JOURNAL OF CELLULAR BIOCHEMISTRY 54 -54
1995
CONFORMATIONS AND LOCATION OF A SUBSTRATE-ANALOG AND PRODUCT BOUND TO THE MUTT ENZYME
DN FRICK , C ABEYGUNAWARDANA , DJ WEBER , MJ BESSMAN
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 208 49 -BIOL
1994
Angela Lam Alicia Hanson Suzanne O'Handley Sourav Mukherjee, PhD Jean Ndjomou Frank Schoenen David J. Weber Johan Neyts Kevin Frankowski Christopher A Dunn Andrea Brancale Marcella Bassetto Marietta Lee Nicholas R. Silvaggi Raicu Group Calender Anne-Frances Miller Michael Sofia Martino Bolognesi Mario Milani