Kaleeckal G. Harikumar, Mphil, PhD
机构: Mayo clinic: Assistant Professor in Medicine
每年引用次数
引用次数
引用: 2,998
H-指数: 32
I10-指数 : 62
出版物: 119
Effect of alcohols on G-protein coupling of serotonin1A receptors from bovine hippocampus
K.G Harikumar , Amitabha Chattopadhyay
Brain Research Bulletin 52 ( 6) 597 -601
18
2000
Use of zonal centrifugation method for the preparation of μ-opioid receptor enriched membranes from bovine corpus striatum
K.V.H Sastry , K.G Harikumar , P Sailaja , M.K Janardana Sarma
Journal of Neuroscience Methods 74 ( 1) 45 -52
1
1997
Modulation of agonist and antagonist interactions in serotonin 1A receptors by alcohols.
K.G Harikumar , Amitabha Chattopadhyay
FEBS Letters 438 ( 1) 96 -100
21
1998
Differential discrimination of G-protein coupling of serotonin1A receptors from bovine hippocampus by an agonist and an antagonist
K.G Harikumar , Amitabha Chattopadhyay
FEBS Letters 457 ( 3) 389 -392
43
1999
An organizational laser safety program at Mayo Clinic in Arizona
Lewis Wesselius , Sharli Frederiksen , Heidi Walton , Tom Pasquariello
International Laser Safety Conference 2007 ( 1) 218 -220
2007
Unveiling GPCR oligomerization and its functional significance using iFRET
Michael R Stoneman , Dammar N Badu , Kaleeckal Harikumar , Laurence J Miller
Biophysical Journal 123 ( 3) 463a -463a
2024
Discovery of Small Molecule Modulators targeting Secretin Receptors
Daniela Dengler , Kaleeckal Harikumar , Sirkku Pollari , Qing Sun
The FASEB Journal 35
2021
Mechanistic insights from the atomic-level quaternary structure of short-lived GPCR oligomers in live cells
Valerica Raicu , Michael Stoneman , Koki Yokoi , Gabriel Biener
2024
Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization
Amitabha Chattopadhyay , K.G. Harikumar
FEBS Letters 391 ( 1-2) 199 -202
104
1996
Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor.
L.J. Miller , M. Dong , K.G. Harikumar , F. Gao
Biochemical Society Transactions 35 ( 4) 709 -712
26
2007
The class B G-protein-coupled GLP-1 receptor: an important target for the treatment of type-2 diabetes mellitus.
L J Miller , P M Sexton , M Dong , K G Harikumar
International Journal of Obesity 4 ( 1)
10
2014
Cholecystokinin-induced satiety, a key gut servomechanism that is affected by the membrane microenvironment of this receptor
A J Desai , M Dong , K G Harikumar , L J Miller
International Journal of Obesity Supplements 6 ( 1)
2
2016
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.
Radostin Danev , Sebastian G B Furness , David M Thal , Denise Wootten
PLOS Biology 19 ( 6)
30
2021
Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor.
Laurence J Miller , Maoqing Dong , Kaleeckal G Harikumar
British Journal of Pharmacology 166 ( 1) 18 -26
14
2012
Roles of cholecystokinin in the nutritional continuum. Physiology and potential therapeutics
Laurence J Miller , Kaleeckal G Harikumar , Denise Wootten , Patrick M Sexton
Frontiers in endocrinology 12 684656
7
2021
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins: insight into mechanisms of G protein selectivity
Jesse Mobbs , Matthew J Belousoff , Kaleeckal G Harikumar , Sarah J Piper
James Geiger, Rick Sexton 2, Zina Al-Sahouri, Ming-Yue Lee, Eugene Chun
Kaleeckal G Harikumar , Laurence J Miller , Oliver Beckstein , Wei Liu
Biophysical Methods Advancing Lipidic Cubic Phase Membrane Proteins Studies 63 -63
2021
Structure of an AMPK complex in an inactive, ATP-bound state
Yan Yan , Somnath Mukherjee , Kaleeckal G Harikumar , Timothy S Strutzenberg
Science 373 ( 6553) 413 -419
54
2021
FRET spectrometry and MD simulations-based modeling resolve the oligomeric structure of a G protein-coupled receptor in live cells
Dammar N Badu , Michael R Stoneman , Gabriel Biener , Thomas D Killeen
Biophysical Journal 123 ( 3) 314a -314a
2024
Environment-sensitive fluorescence of 7-nitrobenz-2-oxa-1, 3-diazol-4-yl (NBD)-labeled ligands for serotonin receptors
Parijat Sarkar , Kaleeckal G Harikumar , Satinder S Rawat , Sanjib Das
Molecules 26 ( 13) 3848 -3848
7
2021
Patrick Sexton Amitabha Chattopadhyay Karsten Melcher Arthur Christopoulos Denise Wootten Ting-Hai Xu Philip S Portoghese H Eric Xu (徐华强), Professor Sebastian G.B. Furness Yan Yan Bart O. Williams Ruben Abagyan Thomas Pucadyil Sarah J Piper Xin Gu Matthew Belousoff Zachary DeBruine Billy KC Chow Radostin Danev Vishwajeet Puri