Achim Aigner
机构: Professor of Clinical Pharmacology, Leipzig University, Faculty of Medicine
每年引用次数
引用次数
引用: 13,806
H-指数: 61
I10-指数 : 154
出版物: 338
The Special AT-rich Binding Protein 1 as a putative therapeutic target in colorectal cancer
U Froemberg , M Rabe , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 386 S25 -S25
2013
Functional expression of the chemosensory cation channel TRPA1 in small cell lung cancer cells and possible implications for tumor-promoting effects of tobacco smoke
EAM Schaefer , M Meister , A Aigner , T Gudermann
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 386 S70 -S70
2013
Depletion of the transcriptional coactivators Megakaryoblastic Leukemia 1 and 2 (MKL1/2) inhibits hepatocellular carcinoma growth by oncogene-induced senescence
V Hampl , C Martin , A Aigner , S Singer
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 386 S57 -S57
2013
Growth regulation in small cell lung cancer via G (q/11)-and G (12/13)-dependent signaling
EAM Schaefer , TRH Buech , M Hauswald , S Stohr
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 385 ( SUPPL 1) 79 -79
2012
Micro-RNA replacement therapy: Nanoparticle-mediated in vivo delivery of miRNA-145 or miRNA-33a exerts antitumor effects in colon carcinoma xenograft mouse models
U Weirauch , AF Ibrahim , M Thomas , K Lange-Gruenweller
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 385 4 -4
2012
Complex biochemical properties of a fibroblast growth factor-binding protein (FGF-BP)
D Schulz , J Hagenbusch , S Abuharbeid , F Czubayko
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 379 10 -10
2009
shRNA-mediated gene targeting reveals a critical role of G-alpha12 and G-alpha13 for human small cell lung cancer cell proliferation and in vivo tumor growth
M Grzelinski , O Pinkenburg , T Buech , M Gold
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 377 25 -26
2008
In vivo toxicity and gene targeting efficacy of polyethylenimine (PEI)/siRNA nanoplexes for therapeutic inhibition of tumor-relevant genes
S Hoebel , A Malek , F Czubayko , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 377 75 -75
2008
G (12/13)-dependent growth of small cell lung cancer
M Grzelinski , T Buech , O Pinkenburg , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 375 35 -35
2007
In vivo targeting of cancer-relevant growth factors in mouse xenografts through direct application of pei-complexed siRNAs
S Hobel , L Dai , B Urban-Klein , R Prinz
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 372 29 -30
2006
Ribozyme double-targeting of the growth factor PTN and its receptor ALK shows synergistic antitumoral effects in vitro and in vivo
M Grzelinski , R Prinz , F Czubayko , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 372 29 -29
2006
Targeting of pleiotrophin (PTN) by ribozymes or RNAi markedly decreases glioblastoma cell proliferation and tumor growth in vitro and in vivo
M Grzelinski , B Urban-Klein , N Bader , S Werth
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 371 R10 -R11
2005
Direct application of PEI-complexed siRNAs-A novel tool for RNAi in vivo
B Urban-Klein , S Werth , M Grzelinski , S Abuharbeid
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 371 R11 -R11
2005
Resistance of SKOV-3 ovarian carcinoma cells towards paclitaxel and rViscumin is dependent on HER-2 (c-erbB2) receptor expression levels
S Abuharbeid , J Apel , G Zugmaier , M Langer
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 371 R10 -R10
2005
RNA interference through application of polyethylenimine-complexed siRNAS allows efficient gene-targeting in vitro and in vivo
B Urban-Klein , F Czubayko , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 369 R55 -R55
2004
Overexpression and function of PTPzeta and pleiotrophin in astrocytomas
U Ulbricht , MA Brockmann , A Aigner , S Muller
ACTA NEUROPATHOLOGICA 106 ( 4) 400 -400
2003
RNA interference (RNAi) and rebozyme-targeting: Two efficient ways to down-regulate gene expression
B Urban-Klein , M Sander , S Abuharbeid , M Grzelinski
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 367 R12 -R12
2003
Breast Cancer-risk factors, prognosis and medical treatment
G Zugmaier , C Knabbe , A Aigner
MEDIZINISCHE WELT-STUTTGART- 54 ( 4) 96 -101
2003
The cytotoxic effects of the anticancer drugs rViscumin and Paclitaxel are dependent on cellular HER-2 (c-erbB2/neu) levels
J Apel , S Abuharbeid , B Moeckel , M Krohn
EUROPEAN JOURNAL OF CANCER 38 S168 -S168
2002
Ribozyme-targeting elucidates the role of the growth factor pleiotrophin (PTN) and of the newly identified PTN-receptor PTN-R/ALK in tumor growth
F Czubayko , C Malerczyk , A Aigner
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 365 R9 -R9
2002