Wenzhen Duan
机构: Professor of Psychiatry & Neuroscience, Johns Hopkins University
主页: jhu.edu
每年引用次数
引用次数
引用: 12,322
H-指数: 52
I10-指数 : 79
出版物: 141
Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models
Benjamin Sredni , Revital Geffen‐Aricha , Wenzhen Duan , Michael Albeck
The FASEB Journal 21 ( 8) 1870 -1883
54
2007
Targeting Sirtuin-1 in Huntington’s disease: Rationale and Current Status
Wenzhen Duan ,
CNS Drugs 27 ( 5) 345 -352
19
2013
Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior
Mark P. Mattson , Sic L. Chan , Wenzhen Duan
Physiological Reviews 82 ( 3) 637 -672
577
2002
Mutant Huntingtin Disrupts the Nuclear Pore Complex
Jonathan C. Grima , J. Gavin Daigle , Nicolas Arbez , Kathleen C. Cunningham
Neuron 94 ( 1) 93 -107.e6
266
2017
Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease
Xiao Zhou , Gang Li , Anna Kaplan , Michael M Gaschler
Human Molecular Genetics 27 ( 9) 1545 -1555
34
2018
Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease
Jing Jin , Qi Peng , Zhipeng Hou , Mali Jiang
Human Molecular Genetics 24 ( 9) 2508 -2527
48
2015
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats
Tamara Ratovitski , Robert N. O’Meally , Mali Jiang , Raghothama Chaerkady
Journal of Proteome Research 16 ( 8) 2692 -2708
47
2017
trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease.
Jinrong Fu , Jing Jin , Robert H. Cichewicz , Serena A. Hageman
Journal of Biological Chemistry 287 ( 29) 24460 -24472
131
2012
Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease
Mark P. Mattson , Devin S. Gary , Sic L. Chan , Wenzhen Duan
Biochemical Society Symposia 67 ( 67) 151 -162
92
2001
Cellular and molecular mechanisms whereby dietary restriction extends healthspan: a beneficial type of stress
Mark P. Mattson , Wenzhen Duan , Ruiqian Wan , Zhihong Guo
Advances in Cell Aging and Gerontology 14 87 -103
5
2003
Resting-state functional MRI reveals altered brain connectivity and its correlation with motor dysfunction in a mouse model of Huntington's disease.
Qiang Li , Gang Li , Dan Wu , Hanbing Lu
Scientific Reports 7 ( 1) 16742 -16742
23
2017
Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington’s Disease
Qi Peng , Bin Wu , Mali Jiang , Jing Jin
PLOS ONE 11 ( 2) e0148839
27
2016
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images.
Jiangyang Zhang , Qi Peng , Qing Li , Neda Jahanshad
NeuroImage 49 ( 3) 2340 -2351
76
2010
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
Yong Cheng , Qi Peng , Zhipeng Hou , Manisha Aggarwal
NeuroImage 56 ( 3) 1027 -1034
40
2011
Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging
Manisha Aggarwal , Wenzhen Duan , Zhipeng Hou , Neal Rakesh
NeuroImage 60 ( 4) 2086 -2095
21
2012
Participation of par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid.
Wenzhen Duan , Zhihong Guo , Mark P. Mattson
Experimental Neurology 165 ( 1) 1 -11
41
2000
Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice.
Wenzhen Duan , ZhiHong Guo , Mark P. Mattson
Journal of Neurochemistry 76 ( 2) 619 -626
163
2001
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
Jaewon Lee , Wenzhen Duan , Mark P. Mattson
Journal of Neurochemistry 82 ( 6) 1367 -1375
763
2002
Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms
Mark P. Mattson , Wenzhen Duan , Zhihong Guo
Journal of Neurochemistry 84 ( 3) 417 -431
329
2003
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.
Wenzhen Duan , Mark P. Mattson
Journal of Neuroscience Research 57 ( 2) 195 -206
412
1999
Mark P. Mattson Zhipeng Hou Susumu Mori Jiangyang Zhang Jaewon Lee Bruce Ladenheim Jean Lud Cadet, M.D. Nicolas Arbez Prof. Dr. Carsten Culmsee Juan Troncoso Roy Cutler Manisha Aggarwal Michael I. Miller Kevin G. Becker Jeffrey D. Rothstein Peter B. Barker Dwight E. Bergles Peggy Nopoulos Eric Ford Athanasios S. Alexandris